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Article
RTG-TOF, a rainbow trout (Oncorhynchus mykiss) cell line with an inducible gene expression system
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Article
Open AccessHigh-throughput proteomic profiling of the fish liver following bacterial infection
High-throughput proteomics was used to determine the role of the fish liver in defense responses to bacterial infection. This was done using a rainbow trout (Oncorhynchus mykiss) model following infection with Ae...
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Article
Open AccessDifferential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon
The potential for alternative plant protein sources to replace limited marine ingredients in fish feeds is important for the future of the fish farming industry. However, plant ingredients in fish feeds contai...
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Article
Open AccessInflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar)
The relationship between fish health and muscle growth is critical for continued expansion of the aquaculture industry. The effect of immune stimulation on the expression of genes related to the energy balance...
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Article
Open AccessTranscriptomic and physiological responses to fishmeal substitution with plant proteins in formulated feed in farmed Atlantic salmon (Salmo salar)
Aquaculture of piscivorous fish is in continual expansion resulting in a global requirement to reduce the dependence on wild caught fish for generation of fishmeal and fish oil. Plant proteins represent a suit...
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Article
Open AccessGenomic organisation analysis of novel immunoglobulin-like transcripts in Atlantic salmon (Salmo salar) reveals a tightly clustered and multigene family
Several novel immunoglobulin-like transcripts (NILTs) which have previously been identified in the salmonid species rainbow trout (Oncorhynchus mykiss) contain either one or two extracellular Ig domains of the V-...
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Article
Open AccessStarvation alters the liver transcriptome of the innate immune response in Atlantic salmon (Salmo salar)
The immune response is an energy demanding process, which has effects in many physiological pathways in the body including protein and lipid metabolism. During an inflammatory response the liver is required to...
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Article
Open AccessDirectional responses following recombinant cytokine stimulation of rainbow trout (Oncorhynchus mykiss) RTS-11 macrophage cells as revealed by transcriptome profiling
The early stages of the immune response are regulated by key cytokines including both interleukin 1β (IL-1β) and interferon-γ (IFN-γ) which stimulate panels of responsive genes via conserved signal transductio...
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Chapter
Fish Cytokine Genes
Relatively few cytokine and cytokine receptor genes had been sequenced in fish prior to EST and genome studies. The number of sequences is rapidly increasing and demonstrates the complexity of the cytokine net...