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Article
Open AccessModulation of gut microbiota composition and predicted metabolic capacity after nutritional programming with a plant-rich diet in Atlantic salmon (Salmo salar): insights across developmental stages
To promote sustainable aquaculture, the formulation of Atlantic salmon (Salmo salar) feeds has changed in recent decades, focusing on replacing standard marine-based ingredients with plant-based alternatives, inc...
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Article
Open AccessFur removal promotes an earlier expression of involution-related genes in mammary gland of lactating mice
Peak lactation occurs when milk production is at its highest. The factors limiting peak lactation performance have been subject of intense debate. Milk production at peak lactation appears limited by the capac...
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Article
Open AccessTranscriptomic response to ISAV infection in the gills, head kidney and spleen of resistant and susceptible Atlantic salmon
Infectious Salmon Anaemia virus (ISAV) is an orthomyxovirus responsible for large losses in Atlantic salmon (Salmo salar) aquaculture. Current available treatments and vaccines are not fully effective, and theref...
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Article
Open AccessTenebrio molitor larvae meal inclusion affects hepatic proteome and apoptosis and/or autophagy of three farmed fish species
Herein, the effect of dietary inclusion of insect (Tenebrio molitor) meal on hepatic pathways of apoptosis and autophagy in three farmed fish species, gilthead seabream (Sparus aurata), European seabass (Dicentra...
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Article
Open AccessSampling the fish gill microbiome: a comparison of tissue biopsies and swabs
Understanding the influence of methodology on results is an essential consideration in experimental design. In the expanding field of fish microbiology, many best practices and targeted techniques remain to be...
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Article
Open AccessThe structural variation landscape in 492 Atlantic salmon genomes
Structural variants (SVs) are a major source of genetic and phenotypic variation, but remain challenging to accurately type and are hence poorly characterized in most species. We present an approach for reliab...
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Article
Harnessing genomics to fast-track genetic improvement in aquaculture
Aquaculture is the fastest-growing farmed food sector and will soon become the primary source of fish and shellfish for human diets. In contrast to crop and livestock production, aquaculture production is deri...
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Article
Open AccessEfficient CRISPR/Cas9 genome editing in a salmonid fish cell line using a lentivirus delivery system
Genome editing is transforming bioscience research, but its application to non-model organisms, such as farmed animal species, requires optimisation. Salmonids are the most important aquaculture species by val...
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Article
Open AccessThe AMPK system of salmonid fishes was expanded through genome duplication and is regulated by growth and immune status in muscle
5′adenosine monophosphate-activated protein kinase (AMPK) is a master regulator of energy homeostasis in eukaryotes. This study identified expansions in the AMPK-α, -β and -γ families of salmonid fishes due to...
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Article
Open AccessHigh-throughput proteomic profiling of the fish liver following bacterial infection
High-throughput proteomics was used to determine the role of the fish liver in defense responses to bacterial infection. This was done using a rainbow trout (Oncorhynchus mykiss) model following infection with Ae...
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Proteomics in Fish and Aquaculture Research
The demand for animal protein for human consumption is currently on the rise fueled mainly by an exponential increase of the world population. The higher demand of fishery products and capture restrictions as ...
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Article
Open AccessSeawater transfer alters the intestinal microbiota profiles of Atlantic salmon (Salmo salar L.)
Atlantic salmon undergo dramatic physiological changes as they migrate from freshwater to the marine environment. Osmoregulatory adaptation is the most crucial change, necessitating functional adaptations of t...
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Article
Open AccessFunctional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture
We describe an emerging initiative - the ‘Functional Annotation of All Salmonid Genomes’ (FAASG), which will leverage the extensive trait diversity that has evolved since a whole genome duplication event in th...
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Article
Open AccessLineage-specific rediploidization is a mechanism to explain time-lags between genome duplication and evolutionary diversification
The functional divergence of duplicate genes (ohnologues) retained from whole genome duplication (WGD) is thought to promote evolutionary diversification. However, species radiation and phenotypic diversificat...
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Article
Open AccessThe complete salmonid IGF-IR gene repertoire and its transcriptional response to disease
The insulin-like growth factor (IGF) receptor (IGF-IR) is necessary for IGF signalling and has essential roles in cellular growth. In teleost fish, two distinct IGF-IR duplicates are conserved called IGF-IRa a...
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Article
Open AccessDevelopment of an Efficient Genome Editing Method by CRISPR/Cas9 in a Fish Cell Line
CRISPR/Cas9 system has been used widely in animals and plants to direct mutagenesis. To date, no such method exists for fish somatic cell lines. We describe an efficient procedure for genome editing in the Chi...
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Article
Open AccessDifferential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon
The potential for alternative plant protein sources to replace limited marine ingredients in fish feeds is important for the future of the fish farming industry. However, plant ingredients in fish feeds contai...
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Article
Open AccessCorrection: Corrigendum: Disparate developmental patterns of immune responses to bacterial and viral infections in fish
During early stages of development vertebrates rely on an immature immune system to fight pathogens, but in non mammalian species few studies have taken an in-depth analysis of the transition from reliance on ...
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Article
Open AccessDisparate developmental patterns of immune responses to bacterial and viral infections in fish
During early stages of development vertebrates rely on an immature immune system to fight pathogens, but in non mammalian species few studies have taken an in-depth analysis of the transition from reliance on ...
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Article
Nasal immunity is an ancient arm of the mucosal immune system of vertebrates
The mucosal surfaces of all vertebrates have been exposed to similar evolutionary pressures for millions of years. In terrestrial vertebrates such as birds and mammals, the nasopharynx-associated lymphoid tiss...
