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    Article

    PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection

    Phenotypic and transcriptional profiling of regulatory T (Treg) cells at homeostasis reveals that T cell receptor activation promotes Treg cells with an effector phenotype (eTreg) characterized by the production ...

    Joseph A. Perry, Lindsey Shallberg, Joseph T. Clark in Nature Immunology (2022)

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    Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system

    An important function of the blood–brain barrier is to exclude pathogens from the central nervous system, but some microorganisms benefit from the ability to enter this site. It has been proposed that Toxoplasma ...

    Christoph Konradt, Norikiyo Ueno, David A. Christian in Nature Microbiology (2016)

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    Article

    Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

    T cells in the brains of Toxoplasma-infected mice are shown to move by Lévy-like walks.

    Tajie H. Harris, Edward J. Banigan, David A. Christian, Christoph Konradt in Nature (2012)