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Article
Open AccessDextran as internal calibrant for N-glycan analysis by liquid chromatography coupled to ion mobility-mass spectrometry
LC–MS is one of the most important tools for the comprehensive characterization of N-glycans. Despite many efforts to speed up glycan analysis via optimized sample preparation (e.g., faster enzyme digestion in co...
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Article
Emergence of low-symmetry foldamers from single monomers
Self-assembly is a powerful method to obtain large discrete functional molecular architectures. When using a single building block, self-assembly generally yields symmetrical objects in which all the subunits ...
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Article
Open AccessShotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides
Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of nat...
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Article
Open AccessThe role of the mobile proton in fucose migration
Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues...
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Chapter
Variant Management and Reuse
Variability management and reuse are important concerns in the development of variant-rich software-intensive systems. In this chapter, we present the SPES XT modeling framework's mechanism to capture the orth...
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Chapter
GaInAs/AlAsSb Quantum Cascade Lasers: A New Approach towards 3-to-5 μm Semiconductor Lasers
At present GaInAs/AlInAs based quantum cascade (QC) lasers represent the state-of-the-art with respect to the short-wavelength (< 5 μm) performance of the QC laser concept. This performance, however, is intrin...
