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Article
Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiation
Cryo-EM structures of the yeast 40S in complex with ribosome-splitting protein ABCE1, along with functional analyses, reveal that the FeS cluster domain undergoes a 150° rotation to dissociate ribosomal subunits.
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Article
Open AccessStructure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry
Ribosome recycling orchestrated by the ATP binding cassette (ABC) protein ABCE1 can be considered as the final—or the first—step within the cyclic process of protein synthesis, connecting translation terminati...
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Chapter
Technology Transfer Concepts
In software engineering, transferring innovative concepts, techniques and methods into the practice of existing organizations is an expensive and complex task. This chapter gives an overview on the transfer of...
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Chapter
Evaluation of the SPES XT Modeling Framework
In software engineering, emprirical evaluations play a major role in discovering the advantages and disadvantages of newly developed methods, techniques, and tools.
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Chapter
Variant Management and Reuse
Variability management and reuse are important concerns in the development of variant-rich software-intensive systems. In this chapter, we present the SPES XT modeling framework's mechanism to capture the orth...
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Chapter and Conference Paper
Extending an IEEE 42010-Compliant Viewpoint-Based Engineering-Framework for Embedded Systems to Support Variant Management
The increasing complexity of today’s embedded systems and the increasing demand for higher quality require a comprehensive engineering approach. The model-based engineering approach that has been developed in ...
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Article
Quality-aware analysis in product line engineering with the orthogonal variability model
Software product line engineering is about producing a set of similar products in a certain domain. A variability model documents the variability amongst products in a product line. The specification of variab...
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Chapter
Application and Evaluation in the Energy Domain
Energy providers in Germany, including grid operators, play an essential role in securing the value chain of almost all business sectors as well as supplying private households with energy.
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Chapter and Conference Paper
Formal Definition of Syntax and Semantics for Documenting Variability in Activity Diagrams
Quality assurance is an important issue in product line engineering. It is commonly agreed that quality assurance in domain engineering requires special attention, since a defect in a domain artifact can affec...
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Chapter and Conference Paper
Towards Goal-Driven Self Optimisation of Service Based Applications
Service based applications are constructed to be easily adaptable to changing environments. This adaptation was primarily investigated with respect to monitoring events, e. g., a service based application is a...
