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  1. Article

    Open Access

    Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy

    The SARS-CoV-2 pandemic has differentially impacted populations across race and ethnicity. A multi-omic approach represents a powerful tool to examine risk across multi-ancestry genomes. We leverage a pandemic...

    Victoria N. Parikh, Alexander G. Ioannidis, David Jimenez-Morales in Nature Communications (2022)

  2. Article

    Open Access

    Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts

    Treatment paradigms for patients with upper tract urothelial carcinoma (UTUC) are typically extrapolated from studies of bladder cancer despite their distinct clinical and molecular characteristics. The advanc...

    Kwanghee Kim, Wenhuo Hu, François Audenet, Nima Almassi in Nature Communications (2020)

  3. Article

    Open Access

    Antibody-mediated phosphatidylserine blockade significantly enhances the efficacy of downstream immune checkpoint inhibition in K1735 mouse melanoma

    **anming Huang, Jian Gong, Dan Ye, Van Nguyen in Journal for ImmunoTherapy of Cancer (2014)

  4. Article

    Open Access

    Targeting of viral interleukin-10 with an antibody fragment specific to damaged arthritic cartilage improves its therapeutic potency

    We previously demonstrated that a single-chain fragment variable (scFv) specific to collagen type II (CII) posttranslationally modified by reactive oxygen species (ROS) can be used to target anti-inflammatory ...

    Chris Hughes, Angelica Sette, Michael Seed in Arthritis Research & Therapy (2014)

  5. Article

    The autonomous animal: Self-governance and the modern subject

    Chris Hughes in Contemporary Political Theory (2013)

  6. No Access

    Article

    Using ion purity scores for enhancing quantitative accuracy and precision in complex proteomics samples

    To accurately determine the quantitative change of peptides and proteins in complex proteomics samples requires knowledge of how well each ion has been measured. The precision of each ions’ calculated area is ...

    Scott J. Geromanos, Chris Hughes in Analytical and Bioanalytical Chemistry (2012)

  7. Article

    Time and World Politics

    Chris Hughes in Contemporary Political Theory (2010)

  8. No Access

    Article

    Real-time Seldinger technique simulation in complex vascular models

    Commercial interventional radiology vascular simulators emulate instrument navigation and device deployment, though none supports the Seldinger technique, which provides initial access to the vascular tree. Th...

    Vincent Luboz, Chris Hughes, Derek Gould in International Journal of Computer Assisted… (2009)

  9. Article

    Open Access

    Identification of Monosialylated N-glycoforms in the CDG Urinome by Ion Mobility Tandem Mass Spectrometry: The Potential for Clinical Applications

    A novel approach of ion mobility tandem mass spectrometry (IMS-MS/MS) is applied to analysis of human glycourinome to obtain carbohydrate pattern data of congenital disorders of glycosylation patient. Overlapp...

    Sergey Y. Vakhrushev, James Langridge, Iain Campuzano, Chris Hughes in Clinical Proteomics (2008)

  10. Chapter

    Better Learning Online?

    Online learning comes up whenever the issue of improving teaching and learning is mentioned in our current educational institutions. Based on multimedia programs and networked computers, it seems very promisin...

    Werner Beuschel, Alfred Bork, Chris Hughes in Building University Electronic Educational… (2000)

  11. No Access

    Article

    The purpose, value and structure of the practicum in higher education: a literature review

    The practicum constitutes an integral part of many professional courses in higher education; and is manifest in several different forms depending on the discipline: field experience, cooperative education, san...

    Greg Ryan, Susan Toohey, Chris Hughes in Higher Education (1996)

  12. No Access

    Article

    Can performance management work in Australian universities?

    Performance appraisal and performance management are much discussed topics at the moment and are widely promoted as tools for maximising the effectiveness of an institution's human resources. This paper will c...

    Chris Hughes, Cathy Sohler in Higher Education (1992)