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Article
Inhibition of thioredoxin 2 by intracellular methylglyoxal accumulation leads to mitochondrial dysfunction and apoptosis in INS-1 cells
To investigate the role of thioredoxin 2 (Trx2) inhibition induced by intracellular methylglyoxal (MGO) in pancreatic beta-cell mitochondrial dysfunction and apoptosis.
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Article
Maternal high-fat diet during pregnancy and lactation affects hepatic lipid metabolism in early life of offspring rat
We investigated whether maternal over-nutrition during pregnancy and lactation affects the offspring’s lipid metabolism at weaning by assessing liver lipid metabolic gene expressions and analysing its mechanis...
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Chapter and Conference Paper
Changes of Blood–Brain Barrier Permeability Following Intracerebral Hemorrhage and the Therapeutic Effect of Minocycline in Rats
Objective: To investigate the changes of blood–brain barrier (BBB) permeability and expressions of VEGF, NGF and HPS70 in brain at different time points following intracerebral hemorrhage (ICH)...
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Article
P27/Kip1 Expression in Gliomas and Its Clinical Significance
Objective: To study p27/Kip1 expression in gliomas and its application value. Methods: Immunohistochemical technique was used to detect the exprssion of p27/Kip1 gene in 48 different malignant grade human brai...