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  1. Article

    Open Access

    Comparison of uric acid reduction and renal outcomes of febuxostat vs allopurinol in patients with chronic kidney disease

    Whether the clinical trial treatment effect of urate-lowering therapy (ULT) in patient with chronic kidney disease (CKD) is generalizable to real-word settings is unclear. This study aimed to compare febuxosta...

    Yueh-Lung Peng, You-Lin Tain, Chien-Te Lee, Yi-Hsn Yang in Scientific Reports (2020)

  2. Article

    Open Access

    Author Correction: Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Cai-Mei Zheng, Jia-Yi Wang, Tzu-Ting Chen, Yun-Chun Wu, Yi-Lien Wu in Scientific Reports (2020)

  3. Article

    Open Access

    Author Correction: Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Tian-Jong Chang, Cai-Mei Zheng, Mei-Yi Wu, Tzu-Ting Chen, Yun-Chun Wu in Scientific Reports (2020)

  4. Article

    Open Access

    Impaired production of immune mediators in dengue virus type 2-infected mononuclear cells of adults with end stage renal disease

    Chronic kidney disease is an epidemiologically identified risk factor for development of severe dengue in dengue-affected patients. However, available data on the immune pathogenesis in end stage renal disease...

    Ing-Kit Lee, Zih-Syuan Yang, Hwee-Yeong Ng, Lung-Chih Li in Scientific Reports (2019)

  5. Article

    Open Access

    Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

    It remains unclear how different uses of angiotensin-converting inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) influence the progression of chronic kidney disease (CKD). This study explored CKD pro...

    Cai-Mei Zheng, Jia-Yi Wang, Tzu-Ting Chen, Yun-Chun Wu, Yi-Lien Wu in Scientific Reports (2019)

  6. Article

    Open Access

    Effect of Statins on Renal Function in Chronic Kidney Disease Patients

    Dyslipidemia is associated with glomerular injury. However, the effect of statins on chronic kidney disease (CKD) progression remains controversial. We aimed to investigate the efficacy of statins for renal pr...

    **-Jen Hu, Mei-Yi Wu, Tsu-Chen Lin, Tzu-Ting Chen, Yun-Chun Wu in Scientific Reports (2018)

  7. Article

    Open Access

    Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population

    This study investigated the characteristics of patients with different chronic kidney disease (CKD) stages according to various body mass index (BMI) categories and determined the influence of BMI in renal fun...

    Tian-Jong Chang, Cai-Mei Zheng, Mei-Yi Wu, Tzu-Ting Chen, Yun-Chun Wu in Scientific Reports (2018)

  8. Article

    Open Access

    Risk factors and their interaction on chronic kidney disease: A multi-centre case control study in Taiwan

    Chronic kidney disease (CKD) is highly prevalent in Taiwan. More than two-thirds of end-stage renal disease is associated with diabetes mellitus (DM) or hypertension (HTN). Therefore, the formulation of a spec...

    Sui-Lung Su, Chin Lin, SenYeong Kao, Chia-Chao Wu, Kuo-Cheng Lu in BMC Nephrology (2015)

  9. No Access

    Article

    Effect of oral ferric citrate on serum phosphorus in hemodialysis patients: multicenter, randomized, double-blind, placebo-controlled study

    Hyperphosphatemia is a common complication in dialysis patients that can be treated by oral phosphate binders. We investigated the efficacy and safety of oral ferric citrate as a phosphate binder for Taiwanese...

    Chien-Te Lee, I-Wen Wu, Shou-Shan Chiang, Yu-Sen Peng in Journal of Nephrology (2015)

  10. No Access

    Article

    Epigenetic histone methylation regulates transforming growth factor β-1 expression following bile duct ligation in rats

    Multiple mechanisms contribute to the liver fibrosis following cholestasis. Recent research has focused on the role of transforming growth factor β-1 (TGF-β1) in the progression of fibrosis. The aim of our stu...

    Shyr-Ming Sheen-Chen, Chung-Ren Lin, Kuan-Hung Chen in Journal of Gastroenterology (2014)

  11. Article

    Melatonin regulates L-arginine transport and NADPH oxidase in young rats with bile duct ligation: role of protein kinase C

    Bile duct ligation (BDL) is a commonly used cholestatic liver disease (CLD) model. We recently found that L-arginine levels were significantly raised by melatonin in young rats with BDL. We hypothesized that prot...

    You-Lin Tain, Chih-Cheng Chen, Chien-Te Lee, Ying-Hsien Kao in Pediatric Research (2013)

  12. Article

    Open Access

    The risk of upper gastrointestinal bleeding in patients treated with hemodialysis: a population-based cohort study

    There are no prior studies that have estimated the risk of upper gastrointestinal bleeding (UGIB) among the dialysis population relative to the general population. The aim of this study was to examine the risk...

    Chien-Chun Kuo, Hsin-Wei Kuo, I-Ming Lee, Chien-Te Lee, Chun-Yuh Yang in BMC Nephrology (2013)

  13. Article

    Open Access

    Discrepancy between effects of carbapenems and flomoxef in treating nosocomial hemodialysis access-related bacteremia secondary to extended spectrum beta-lactamase producing klebsiella pneumoniaein patients on maintenance hemodialysis

    Hemodialysis (HD) patients are susceptible to extended spectrum beta-lactamase (ESBL)-producing bacterial infections. Because the optimal treatment and clinical significance of ESBL-producing Klebsiella pneumonia...

    Chih-Chao Yang, Shau-Hsuan Li, Feng-Rong Chuang, Chih-Hung Chen in BMC Infectious Diseases (2012)

  14. No Access

    Article

    A potential salvage therapy for refractory renal cyst infection in patients with autosomal dominant polycystic kidney disease

    Chih-Chao Yang, Feng-Rong Chuang, **-Bor Chen in Clinical and Experimental Nephrology (2012)

  15. No Access

    Article

    Propofol-induced vascular permeability change is related to the nitric oxide signaling pathway and occludin phosphorylation

    The present study was undertaken to elucidate the mechanism of intra-arterial propofol-induced vascular permeability change resulting in tissue edema. The mechanism of propofol-induced hyperpermeability was ex...

    Yi-Shen Chen, Kuan-Hung Chen, Chien-Cheug Liu in Journal of Biomedical Science (2007)

  16. No Access

    Article

    Hepatitis C virus infection among short-term intravenous drug users in southern Taiwan

    The purpose of this study was to determine the correlation between the prevalence of hepatitis C virus (HCV) infection with duration of drug use and other risk factors among drug users. This survey covered 899...

    Chai-Jan Chang, Chun-Hui Lin, Chien-Te Lee in European Journal of Epidemiology (1999)

  17. No Access

    Article

    Muscle Force and Bone Mineral Density after Parathyroidectomy and Subcutaneous Autotransplantation for Secondary Hyperparathyroidism

    The object of this study was to determine the muscle force and bone mineral density (BMD) of patients with secondary hyperparathyroidism before and 3 months after operation. Thirty-nine patients with secondar...

    Fong-Fu Chou, Chiang Hsuan Lee, Chien Te Lee in World Journal of Surgery (1999)