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Article
Open AccessAberrant expression of a stabilized β-catenin mutant in keratocytes inhibits mouse corneal epithelial stratification
We previously reported that genetic deletion of β-catenin in mouse corneal keratocytes resulted in precocious corneal epithelial stratification. In this study, to strengthen the notion that corneal keratocyte-...
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Article
Open AccessImpaired healing of cornea incision injury in a TRPV1-deficient mouse
The present study attempts to elucidate the role of TRPV1 cation channel receptor on primary repair in an incision-wounded mouse cornea in vivo. Previous study revealed that blocking TRPV1 suppressed myofibrob...
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Article
Open AccessWakayama symposium: role of canonical Notch signaling in conjucntival goblet cell differentiation and dry eye syndrome
This review summarizes a recent finding regarding the intrinsic canonical Notch signaling pathway in regulating normal ocular surface morphogenesis and its role in the pathogenesis of goblet cell deficiency-as...
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Article
Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection
RNA nanoparticles derived from the three-way junction (3WJ) of the pRNA of bacteriophage phi29 DNA packaging motor were previously found to be thermodynamically stable. As the nanoparticles could have potentia...
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Protocol
Lumican Promotes Corneal Epithelial Wound Healing
Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and is also present in the connective tissues of other organs and embryonic corneal stroma as a glycoprotein. In no...
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Article
Corneal morphogenesis during development and wound healing
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Chapter and Conference Paper
Evaluating Emotive Character Animations Created with Procedural Animation
How to create effective body animations for virtual agents with emotions remains the state of the art for human animators and a great challenge for computer scientists. In this paper, we propose to use a model...
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Chapter and Conference Paper
Verification of Expressiveness of Procedural Parameters for Generating Emotional Motions
Body movements are crucial for emotion expression of a virtual agent. However, the perception of expressiveness of an animation has always been a subjective matter. Research in psychology has asked professiona...
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Article
Roles of lumican and keratocan on corneal transparency
Lumican and keratocan are members of the small leucine-rich proteoglycan (SLRP) family, and are the major keratan sulfate (KS) proteoglycans in corneal stroma. Both lumican and keratocan are essential for norm...