11 Result(s)
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Chen Song
Life Sciences, general
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Article
Open AccessStructural insights into VAChT neurotransmitter recognition and inhibition
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Article
Author Correction: Substrate and drug recognition mechanisms of SLC19A3
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Article
Substrate and drug recognition mechanisms of SLC19A3
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Article
SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis
Solute carrier family 25 member 51 (SLC25A51) was recently identified as the mammalian mitochondrial NAD+ transporter essential for mitochondria functions. However, the role of SLC25A51 in human disease, such ...
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Article
Open AccessThe phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation
During interphase, the newly duplicated pairs of centrosomes are held together by a centrosome linker, and the centrosome separation needs the disruption of this linker to induce the duplicated centrosomes sep...
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Article
Open AccessEleutheroside E supplementation prevents radiation-induced cognitive impairment and activates PKA signaling via gut microbiota
Radiation affects not only cognitive function but also gut microbiota. Eleutheroside E (EE), a principal active compound of Acanthopanax senticosus, has a certain protective effect on the nervous system. Here,...
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Article
PYCR, a key enzyme in proline metabolism, functions in tumorigenesis
Pyrroline-5-carboxylate reductase (PYCR), the last enzyme in proline synthesis that converts P5C into proline, was found promoting cancer growth and inhibiting apoptosis through multiple approaches, including ...
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Article
The Confidence Database
Understanding how people rate their confidence is critical for the characterization of a wide range of perceptual, memory, motor and cognitive processes. To enable the continued exploration of these processes,...
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Article
Structure of the mechanosensitive OSCA channels
Mechanosensitive ion channels convert mechanical stimuli into a flow of ions. These channels are widely distributed from bacteria to higher plants and humans, and are involved in many crucial physiological pro...
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Article
A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo
DNA origami-based nanorobot presents thrombin to cause tumor infarction after specific recognition of a tumor vessel marker.
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Article
Open AccessKMT2A promotes melanoma cell growth by targeting hTERT signaling pathway
Melanoma is an aggressive cutaneous malignancy, illuminating the exact mechanisms and finding novel therapeutic targets are urgently needed. In this study, we identified KMT2A as a potential target, which prom...
