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  1. Article

    Open Access

    Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways

    Myelin destruction and oligodendrocyte (OL) death consequent to metabolic stress is a feature of CNS disorders across the age spectrum. Using cells derived from surgically resected tissue, we demonstrate that ...

    Milton Guilherme Forestieri Fernandes, Julia **ao Xuan Luo… in Communications Biology (2021)

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  2. Article

    Open Access

    Author Correction: Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Charles P. Couturier, Shamini Ayyadhury, Phuong U. Le, Javad Nadaf… in Nature Communications (2020)

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  3. Article

    Open Access

    Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

    Cancer stem cells are critical for cancer initiation, development, and treatment resistance. Our understanding of these processes, and how they relate to glioblastoma heterogeneity, is limited. To overcome the...

    Charles P. Couturier, Shamini Ayyadhury, Phuong U. Le, Javad Nadaf… in Nature Communications (2020)

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  4. No Access

    Article

    MAFG-driven astrocytes promote CNS inflammation

    Multiple sclerosis is a chronic inflammatory disease of the CNS1. Astrocytes contribute to the pathogenesis of multiple sclerosis2, but little is known about the heterogeneity of astrocytes and its regulation. He...

    Michael A. Wheeler, Iain C. Clark, Emily C. Tjon, Zhaorong Li… in Nature (2020)