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Article
Open AccessAbnormal EEG microstates in Alzheimer’s disease: predictors of β-amyloid deposition degree and disease classification
Electroencephalography (EEG) microstates are used to study cognitive processes and brain disease-related changes. However, dysfunctional patterns of microstate dynamics in Alzheimer's disease (AD) remain uncer...
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Article
Open AccessDevelopment and validation of a machine learning-based predictive model for assessing the 90-day prognostic outcome of patients with spontaneous intracerebral hemorrhage
Spontaneous intracerebral hemorrhage (sICH) is associated with significant mortality and morbidity. Predicting the prognosis of patients with sICH remains an important issue, which significantly affects treatm...
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Article
m6A mRNA methylation regulates the ERK/NF-κB/AKT signaling pathway through the PAPPA/IGFBP4 axis to promote proliferation and tumor formation in endometrial cancer
N6-methyladenosine (m6A) mRNA methylation has been considered a gene modulatory mechanism involved in disease progression and carcinogenesis. Herein, we aimed to explore the specific mechanism of m6A mRNA methyla...
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Article
An adaptive mesh refinement method for indirectly solving optimal control problems
The indirect solution of optimal control problems (OCPs) with inequality constraints and parameters is obtained by solving the two-point boundary value problem (BVP) involving index-1 differential-algebraic eq...
