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  1. Article

    Open Access

    Structural importance of the C-terminal region in pig aldo-keto reductase family 1 member C1 and their effects on enzymatic activity

    Pig aldo-keto reductase family 1 member C1 (AKR1C1) belongs to AKR superfamily which catalyzes the NAD(P)H-dependent reduction of various substrates including steroid hormones. Previously we have reported two ...

    Minky Son, Chanin Park, Seul Gi Kwon, Woo Young Bang… in BMC Structural Biology (2015)

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  2. No Access

    Article

    New insights in the activation of human cholesterol esterase to design potent anti-cholesterol drugs

    Primary hypercholesterolemia is the root cause for major health issues like coronary heart disease and atherosclerosis. Regulating plasma cholesterol level, which is the product of biosynthesis as well as diet...

    Shalini John, Sundarapandian Thangapandian, Prettina Lazar… in Molecular Diversity (2014)