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Article
Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication
During DNA replication, nucleosomes are rapidly assembled on newly synthesized DNA to restore chromatin organization. Asf1, a key histone H3-H4 chaperone required for this process, is phosphorylated by Tousled...
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Article
A unique binding mode enables MCM2 to chaperone histones H3–H4 at replication forks
Chromatin reassembly after replication requires recycling of old and deposition of new histones. Structural insights into how MCM2, part of the replicative helicase, interacts with H3–H4 suggest a function in ...
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Article
Histone chaperone networks sha** chromatin function
Chromatin integrity and functionality is governed by the controlled assembly and disassembly of nucleosomes.
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