18 Result(s)

Reference Work Entry In depth

Computational Models of Motor Pools

C. J. Heckman in Encyclopedia of Computational Neuroscience (2022)

Chapter and Conference Paper

Canonical Motor Microcircuit for Control of a Rat Hindlimb

This work focuses on creating a controller for the hip joint of a rat using a canonical motor microcircuit. It is thought that this circuit acts to modulate motor neuron activity at the output stage. We first ...

Clayton Jackson, William R. P. Nourse, C. J. Heckman… in Biomimetic and Biohybrid Systems (2022)

Chapter

The Cellular Basis for the Generation of Firing Patterns in Human Motor Units

Motor units, which comprise a motoneuron and the set of muscle fibers it innervates, are the fundamental neuromuscular transducers for all motor commands. The one to one relationship between a motoneuron and i...

Obaid U. Khurram, Gregory E. P. Pearcey, Matthieu K. Chardon… in Vertebrate Motoneurons (2022)

Article

To protect or not to protect: examining reasons for sun protection among young women at risk for skin cancer

We aimed to further the understanding of the low rates of sun protection in young women at risk for skin cancer. Six-hundred-sixty-one daily diary entries were received via text message over 14 days from 56 yo...

M. V. Auerbach, C. J. Heckman, S. Darlow in Journal of Behavioral Medicine (2018)

Article

Refinement of measures to assess psychosocial constructs associated with skin cancer risk and protective behaviors of young adults

The study’s purpose was to select/refine measures assessing psychosocial constructs associated with skin cancer risk/protective behaviors. Cognitive interviewing was conducted with twenty participants locally,...

C. J. Heckman, E. Handorf, S. D. Darlow, A. L. Yaroch… in Journal of Behavioral Medicine (2017)

Reference Work Entry In depth

Computational Models of Motor Pools

C. J. Heckman in Encyclopedia of Computational Neuroscience (2015)

Chapter and Conference Paper

Reconfiguration of the Electrical Properties of Motoneurons to Match the Diverse Demands of Motor Behavior

Though long considered simple “threshold and fire” cells, motoneurons are now known to exhibit a wide range of electrical states. These state changes are induced by the interactions between three types of inpu...

C. J. Heckman, Michael D. Johnson in Progress in Motor Control (2014)

Living Reference Work Entry In depth

Computational Models of Motor Pools

C. J. Heckman in Encyclopedia of Computational Neuroscience

Reference Work Entry In depth

Muscle

C. J. Heckman, Eric Perreault, Thomas Sandercock, Huub Maas in Encyclopedia of Neuroscience (2009)

Reference Work Entry In depth

Muscle: The Molecular Motor

C. J. Heckman in Encyclopedia of Neuroscience (2009)

Article

Intrinsic electrical properties of spinal motoneurons vary with joint angle

The dendrites of spinal motoneurons amplify synaptic inputs to a marked degree through persistent inward currents (PICs). Dendritic amplification is subject to neuromodulatory control from the brainstem by axo...

Allison S Hyngstrom, Michael D Johnson, Jack F Miller, C J Heckman in Nature Neuroscience (2007)

Article

The calcium binding proteins calbindin, parvalbumin, and calretinin have specific patterns of expression in the gray matter of cat spinal cord

Calcium binding proteins (CBPs) regulate intracellular levels of calcium (Ca²⁺) ions. CBPs are particularly interesting from a morphological standpoint, because they are differentially expressed in certain sub-po...

Roberta Anelli, C. J. Heckman in Journal of Neurocytology (2005)

Chapter

Spinal Mechanisms for Control of Muscle Length and Force

All motor commands from the central nervous system (CNS) are expressed through changes in the magnitude of neural excitation of skeletal muscle. These changes in muscle excitation give rise to force generation...

C. J. Heckman, W. Zev Rymer in Neuroscience in Medicine (2003)

Chapter

Active Dendritic Conductances Influence the Relations Between Synaptic Input and the Current-Voltage Relation of Adult Spinal Motoneurons

Techniques for recording directly from dendrites of CNS neurons require in vitro preparations (e.g. Spruston et al. 1995). However, we have developed a combined computational/experimental approach that allows ...

Robert H. Lee, C. J. Heckman in Computational Neuroscience (1998)

Article

Motor unit recruitment patterns during reflex compensation of muscle yield investigated by computer simulations

 An important function of the stretch reflex in the soleus muscle in the decerebrate cat preparation is to compensate for the tendency of muscle suddenly to yield during ramp increases in length. As the level ...

Djordje Boskov, C. J. Heckman in Biological Cybernetics (1996)

Article

Effect of reversible dorsal cold block on the persistence of inhibition generated by spinal reflexes

The effects of bilateral focal cooling of dorsolateral thoracic spinal cord on segmental reflex pathways to the triceps surae muscles were assessed in decerebrate cats from the reflex forces produced by single...

J. F. Miller, K. D. Paul, B. Jiang, W. Z. Rymer… in Experimental Brain Research (1995)

Article

Differences between steady-state and transient post-synaptic potentials elicited by stimulation of the sural nerve

In cat medial gastrocnemius motoneurons, single stimuli to the cutaneous sural nerve evoke a post-synaptic potential with a mixture of depolarization and hyperpolarization, depolarization being dominant in typ...

C. J. Heckman, J. F. Miller, M. Munson, W. Z. Rymer in Experimental Brain Research (1992)