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Article
Klinefelter Bone Microarchitecture Evolution with Testosterone Replacement Therapy
Klinefelter Syndrome (KS) patients, defined by a 47 XXY karyotype, have increased risk of fragility fractures. We have assessed bone microarchitecture by high resolution peripheral quantitative CT (HR-pQCT) at...
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Article
Anti-osteoporotic treatments in France: initiation, persistence and switches over 6 years of follow-up
Limited information is available on anti-osteoporotic treatment initiation patterns in France. In 2006–2013, the most frequently prescribed first-line treatment class for osteoporosis was represented by bispho...
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Article
Has sclerostin a true endocrine metabolic action complementary to osteocalcin in older men?
The reported association between sclerostin and diabetes mellitus or abdominal fat may be biased by body size and bone mass. In older men, the association between serum sclerostin levels and metabolic syndrome...
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Article
SFMCP 2014 – La fracture de fatigue : et après ?
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Article
Serum sclerostin: the missing link in the bone-vessel cross-talk in hemodialysis patients?
We found for the first time that in maintenance hemodialysis patients, higher sclerostin serum level was associated with severe abdominal aortic calcification (AAC). In addition, cortical bone microarchitectur...
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Article
Osteoid osteoma is an osteocalcinoma affecting glucose metabolism
Osteocalcin is a hormone secreted by osteoblasts, which regulates energy metabolism by increasing β-cell proliferation, insulin secretion, insulin sensitivity, and energy expenditure. This has been demonstrate...
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Article
Systemic bone effects of biologic therapies in rheumatoid arthritis and ankylosing spondylitis
Inflammatory joint diseases are responsible of chronic systemic inflammation, joint degradations, deformities, and altered quality of life. Patients suffering from chronic rheumatic diseases also present incre...