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Article
Preservation of 34S-enriched sulfides in fossil sulfate-methane transition zones: new evidence from Miocene outcrops of the northern Apennines (Italy)
We provide new evidence of the preservation of 34S-enriched signals in methane seep-impacted sediments from two onshore Miocene outcrops located in the northern Apennines (Italy). Selected outcrops include methan...
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Article
SPREADing the stroke units? PROSIT!
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Article
Growth advantage of chronic myeloid leukemia CFU-GM in vitro : survival to growth factor deprivation, possibly related to autocrine stimulation, is a more common feature than hypersensitivity to GM-CSF/IL3 and is efficiently counteracted by retinoids ± α-interferon
Bcr/abl fusion gene, in experimental models, induces survival to growth factor deprivation and hypersensitivity to IL3. However, conflicting data were reported about chronic myeloid leukemia (CML) progenitors....
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Article
Overweight as an adverse prognostic factor for non-Hodgkin's lymphoma patients receiving high-dose chemotherapy and autograft
Despite detailed evaluation of disease-associated prognostic factors, little is known about the impact of overweight in autograft programs for non-Hodgkin's lymphoma (NHL) patients. In order to address this is...
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Chapter and Conference Paper
Instrumental Diagnosis and Treatment of Acute Ischemic Stroke: The Clinician’s Perspective
It is difficult to estimate the impact of experimental work on mechanisms of induction and protection of cellular damage in the “real world” of neurological diseases. This is particularly difficult for ischemi...
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Article
High-dose contrast-enhanced MRI in multiple sclerosis
Contrast-enhanced MRI is effective for assessing disease activity in multiple sclerosis (MS) and may provide an outcome measure for testing the efficacy of treatment in clinical trials. To compare the sensitiv...
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Chapter and Conference Paper
Thrombolysis in Acute Ischemic Stroke
Thrombolysis is an attractive but potentially dangerous therapy for cerebral ischemia: it is capable of dissolving an arterial thrombus, but can also transform a pale infarct into a hematoma and/or may cause s...
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Chapter and Conference Paper
Haemorrhagic transformation of acute cerebral ischaemia on CT
In a continuous series of 132 patients with ischaemic stroke studied in the acute phase, we assessed the occurrence and CT appearances of haemorrhagic transformation (HI) related to clinical outcome. Fiftyseve...
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Chapter and Conference Paper
European Cooperative Acute Stroke Study: Trial Protocol
The European Cooperative Acute Stroke Study (ECASS) is a double-blind, randomized placebo controlled trial of rt-PA (alteplase) in acute ischemic hemispheric stroke in which thrombolysis is initiated 1–6 h fol...
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Article
Fourth meeting of the European Neurological Society 25–29 June 1994 Barcelona, Spain
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Article
Antiphospholipid antibodies and cerebral artery dissection: Two frequent causes of brain ischemia in young adults
As part of a multicenter study on ischemic stroke in the young, we report the occurrence of high antiphospholipid antibody (aPLs) levels and cerebral dissection in 75 patients. These represent the two most fre...
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Chapter and Conference Paper
What Are We Learning from Clinical Trials in Acute Cerebral Ischemia?
At the beginning of the 1990s we can make a long list of studies on various pharmacological tools and approaches to the treatment of acute cerebral ischemia, such as osmotics, steroids, vasodilators, hemodilut...
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Chapter and Conference Paper
Clinical Outcome of Acute Ischemic Stroke: Prospective Angiographic Studies
Studies of supratentorial ischemic stroke have shown that the sooner an angiography is performed, the easier it is to detect the middle cerebral artery (MCA) trunk or branch occlusion [2, 3, 6]. Early angiogra...
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Chapter
Pharmacological Approach to Acute Ischemic Stroke
Negative results of trials on the pharmacological treatment of acute ischemic stroke have represented a constant, distressing experience for the clinicians involved. In fact, none of the drugs effective in pre...
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Chapter and Conference Paper
Early Treatment of Stroke in Man
According to data from the Rochester study, both stroke incidence and mortality had declined more than 50%, and long-term survival had improved over 70% from 1945–1949 to 1970–1974 (Whisnant 1983). However, no...
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Chapter and Conference Paper
The Prognosis of Stroke in the Elderly
Few studies have been focused on the prognosis of cerebrovascular disease in patients aged 65 years and over. Predictors of stroke-associated mortality were studied by Kay-Tee et al. [11], whose cohort of pati...
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Article
Ischaemic supratentorial stroke: angiographic findings in patients examined in the very early phase
Eighty patients were studied by angiography within 6 h of an ischaemic stroke. Angiography was carried out with digital equipment and was usually limited to the vascular territory responsible for the neurologi...
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Chapter and Conference Paper
Prognosis of Cerebrovascular Disease
Cerebral ischaemia, although easily recognizable from the medical history and neurological examination, nevertheless, remains an intriguing and fascinating pathophysiological entity. Close observation of the a...
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Chapter and Conference Paper
Zur Prognose cerebrovaskulärer Erkrankungen
Obwohl durch Anamnese und neurologische Untersuchung leicht diagnostizier-bar, bleibt die cerebrale Ischämie dennoch eine fesselnde und faszinierende pathophysiologische Entität.
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Article
Ischaemic intermittent claudication of the masticatory muscles: two case reports
Intermittent claudication of the masticatory muscles is an unusual symptom sometimes described in association with temporal arteritis. We describe here two cases where this symptom was due to insufficient bloo...
