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Article
Open AccessGenome-wide expression and response to exposure-based psychological therapy for anxiety disorders
Exposure-based psychological treatments for anxiety have high efficacy. However, a substantial proportion of patients do not respond to therapy. Research examining the potential biological underpinnings of the...
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Article
Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns
Exposure to maternal diabetes during fetal growth is a risk factor for the development of type II diabetes (T2D) in later life. Discovery of the mechanisms involved in this association should provide valuable ...
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Article
Erratum: Serotonin tranporter methylation and response to cognitive behaviour therapy in children with anxiety disorders
Correction to: Translational Psychiatry (2014) 4, e444; doi:10.1038/tp.2014.83; published online 16 September 2014 Following publication, the authors noticed that there was a mistake in the title of their pape...
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Article
Erratum: Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain
Correction to: Translational Psychiatry (2014) 4, e434; doi:10.1038/tp.2014.80; published online 2 September 2014 Following publication, the authors noticed that the error bars in Figure 1 showed Standard Devi...
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Article
Open AccessSerotonin tranporter methylation and response to cognitive behaviour therapy in children with anxiety disorders
Anxiety disorders that are the most commonly occurring psychiatric disorders in childhood, are associated with a range of social and educational impairments and often continue into adulthood. Cognitive behavio...
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Article
Open AccessPrenatal maternal immune activation causes epigenetic differences in adolescent mouse brain
Epigenetic processes such as DNA methylation have been implicated in the pathophysiology of neurodevelopmental disorders including schizophrenia and autism. Epigenetic changes can be induced by environmental e...
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Article
Open AccessMethylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits
Autism spectrum disorder (ASD) defines a group of common, complex neurodevelopmental disorders. Although the aetiology of ASD has a strong genetic component, there is considerable monozygotic (MZ) twin discord...
