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  1. No Access

    Article

    N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial

    Current treatments for adolescent alcohol use disorder (AUD) are mainly psychosocial and limited in their efficacy. As such, pharmacotherapies are being investigated as potential adjunctive treatments to bolst...

    Anna E. Kirkland, Brittney D. Browning, ReJoyce Green, Helen Liu… in Neuropsychopharmacology (2023)

  2. No Access

    Article

    The lateral habenula is not required for ethanol dependence-induced escalation of drinking

    The lateral habenula (LHb) is an epithalamic nuclei that has been shown to signal the aversive properties of ethanol. The present study tested the hypothesis that activity of the LHb is required for the acquis...

    Todd B. Nentwig, Dylan T. Vaughan, Kevin M. Braunscheidel… in Neuropsychopharmacology (2022)

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    Article

    Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies

    Alcohol misuse and alcohol use disorder (AlUD) have neurobiological consequences. This meta-analysis of proton magnetic resonance spectroscopy (MRS) studies aimed to assess the differences in brain metabolite ...

    Anna E. Kirkland, Brittney D. Browning, ReJoyce Green… in Molecular Psychiatry (2022)

  4. Article

    Open Access

    Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use

    Growing evidence suggests that the glucagon-like peptide-1 (GLP-1) system is involved in mechanisms underlying alcohol seeking and consumption. Accordingly, the GLP-1 receptor (GLP-1R) has begun to be studied ...

    Mehdi Farokhnia, Samantha J. Fede, Erica N. Grodin… in Scientific Reports (2022)

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