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Article
Topology of the signal transduction of the G protein-coupled somatostatin receptor sst2 in human glioma cells
By a dual approach, using electron microscopy and biochemical techniques, we investigated the topology of the somatostatin receptor sst2 with its inhibitory G protein Giα after ligand-induced stimulation and int...
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Article
The presence of N-acetylneuraminic acid in Malpighian tubules of larvae of the cicada Philaenus spumarius
Sialic acid-containing glycoconjugates are generally considered to be unique to the deuterostomes, a lineage of the animal kingdom which includes animals from the echinoderms up to the vertebrates. There are, ...
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Article
Rat thymic epithelial cells in vitro and in situ: characterization by immunocytochemistry and morphology
A new method for the long-term culture of pure rat thymic epithelial cells was established. The cultures were characterized by immunocytochemistry, electron microscopy and proliferation assays. Non-epithelial ...
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Article
Visualization of neuropeptide-binding sites on individual telencephalic neurons of the rat
The identification of high-affinity binding sites for neuropeptides on individual target cells is a prerequisite when studying the sites of action and the manner in which peptides act as neuromediators. In sit...
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Article
Somatostatin binding sites on rat diencephalic astrocytes
Using a somatostatin-gold conjugate of known biological activity, high affinity binding sites for this neuropeptide were visualized at cellular resolution on cultured diencephalic astrocytes and on frozen sect...
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Article
Somatostatin-binding sites on rat telencephalic astrocytes
Using a somatostatin-gold conjugate as ligand, high-affinity binding sites for this neuropeptide were demonstrated at three levels: (i) cultured astrocytes from rat cortex, (ii) hippocampal slice cultures, and...
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Article
The mouse neural plate as starting material for studying neuronal differentiation in vitro
Tissue from the mouse neural plate and neural tube was studied, by light and electron microscopy, as starting material for tissue culture.
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Article
Different populations of granules and their distribution in the hypothalamo-neurohypophysial tract of the rat under various experimental conditions
A morphometric evaluation of electron micrographs has been carried out from neurosecretory terminals in the neurohypophysis and from the supraoptic and paraventricular nuclei in normal male and female rats as ...
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Article
On the sexual segment of the kidney in the snake (Natrix natrix)
The sexual segment of the kidney of Natrix natrix has been investigated cytochemically, light microscopically and ultrastructurally. The sexual segment, which seems to be an important accessory sexual organ, has ...
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Article
Über das Apikalorgan (Statocyste) der Ctenophore Pleurobrachia pileus
The statocyst of the ctenophore, Pleurobrachia pileus, was studied by light and electron microscopy and by histochemical techniques. The following results, which partly extend the findings of other authors were o...
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Article
Exocytose im Hinterlappen der Hypophyse
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Electron microscopical investigations of the neurohypophysis in rat and trout reveal that exocytosis of neuro...
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