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Open AccessMolecular and functional heterogeneity in dorsal and ventral oligodendrocyte progenitor cells of the mouse forebrain in response to DNA damage
In the develo** mouse forebrain, temporally distinct waves of oligodendrocyte progenitor cells (OPCs) arise from different germinal zones and eventually populate either dorsal or ventral regions, where they ...
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Article
Open AccessNovel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation
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Christopher Watkin: Difficult atheism: post-theological thinking in Alain Badiou, Jean-Luc Nancy and Quentin Meillassoux
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Saturating the Phenomenon: Marion and Buber
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Balloon cells in human cortical dysplasia and tuberous sclerosis: isolation of a pathological progenitor-like cell
Neural stem cells are present in the human post-natal brain and are important in the development of brain tumours. However, their contribution to non-neoplastic human disease is less clear. We have tested the ...
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Article
Cytogenetic analysis of paediatric astrocytoma using comparative genomic hybridisation and fluorescence in-situ hybridisation
Little is known about the cytogenetic and molecular genetic events that lead to the formation of paediatric astrocytoma. We have analysed 57 paediatric astrocytoma (WHO grades I–IV) using comparative genomic h...
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Factors Associated with Early Attrition from Psychosocial Rehabilitation Programs
This study aimed to identify characteristics associated with early dropout from a vocationally oriented psychosocial rehabilitation (PSR) program for clients with severe mental illness. The sample consisted of...
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Article
Intravascular Inflammatory Myofibroblastic Tumors in Infancy
Inflammatory myofibroblastic tumor (IMT), previously described as inflammatory pseudotumor, can occur at any age but is a recognized soft tissue tumor of childhood. Less than 10 previous cases have been descr...
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Article
GATA3 haplo-insufficiency causes human HDR syndrome
Terminal deletions of chromosome 10p result in a DiGeorge-like phenotype that includes hypoparathyroidism, heart defects, immune deficiency, deafness and renal malformations1. Studies in patients with 10p deletio...
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Article
EagI andNotI linking clones from human chromosomes 11 and Xp
EagI andNotI linking libraries were prepared in the lambda vector, EMBL5, from the mouse-human somatic cell hybrid 1W1LA4.9, which contains human chromosomes 11 and Xp as the only human component. Individual clo...
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Article
A common molecular basis for three inherited kidney stone diseases
KIDNEY stones (nephrolithiasis), which affect 12% of males and 5% of females in the western world, are familial in 45% of patients1,2 and are most commonly associated with hypercalciuria1. Three disorders of hype...
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Ernest Hemingway: Men With, or Without, Women
‘There are, however, no women in his books!’ wrote Leslie Fiedler in Love and Death in the American Novel (1960). The ‘however’ was central to Fiedler’s argument. Hemingway, he believed, was much addicted to desc...