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Article
Dataset for the reporting of neoplasms of the heart, pericardium, and great vessels: recommendations from the International Collaboration on Cancer Reporting (ICCR)
The International Collaboration on Cancer Reporting (ICCR) was founded by major pathology organizations from around the world to produce internationally standardized and evidence-based datasets for pathologis...
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Article
Open AccessPost-mortem study of the association between cardiac iron and fibrosis in transfusion dependent anaemia
Heart failure related to cardiac siderosis remains a major cause of death in transfusion dependent anaemias. Replacement fibrosis has been reported as causative of heart failure in siderotic cardiomyopathy in ...
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Article
Open AccessNon-invasive assessment of interstitial myocardial fibrosis in pressure-overload left ventricular hypertrophy
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Chapter
Restrictive Cardiomyopathy
Restrictive cardiomyopathy is a condition characterized by normal left ventricular cavity size and systolic function but with increased myocardial stiffness [1]. This makes the ventricle incompliant and fill p...
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Chapter
Diseases of the Aorta
Acute aortic dissection is a surgical emergency that requires accurate diagnosis and prompt management. A number of classifications exist, the simplest of which classifies aortic dissection according to the lo...
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Chapter
Pericardial Disease
The pericardium consists of two layers, a visceral layer lined by mesothelial cells and a parietal or fibrous layer lined also by mesothelial cells but with attached fat and fibrous tissue. The mesothelial lay...
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Chapter
Tricuspid Valve
The morphologically right atrioventricular valve has three leaflets (tricuspid): septal, inferior (mural), and anterosuperior which are separated from each other by anteroseptal, superoinferior, and inferosept...
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Chapter
Valve Substitutes
For the last 40 years, valve replacement with various substitutes in patients with severe valve dysfunction has been practiced, particularly in those with unrepairable valve deformation [1].
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Chapter
Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary cardiac muscle disorder with unique pathophysiology, heterogeneous expression, and diverse clinical presentations. It is probably the most common genetically tran...
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Pulmonary Hypertension
Pulmonary hypertension describes raised pulmonary circulatory pressure, venous or arterial. Venous pulmonary hypertension is more common in daily practice than primary arterial hypertension.
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Chapter
Cardiac Tumors
Cardiac tumors are rarely suspected clinically but usually appear as unexpected findings when patients are investigated for syncope, breathlessness, thromboembolism, or constitutional manifestations such as co...
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Chapter
Pulmonary Valve
The pulmonary valve lies anterior and to the left of the aortic valve. The three pulmonary leaflets assume the shape of half moons (semi-lunar) and are similar but usually not equal in size. The right and left...
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Chapter
Mitral Valve
The mitral valve is composed of two leaflets, an annulus, chordae tendineae, and two papillary muscles. The anterior (aortic) leaflet is attached to the root of the aorta in direct continuity with the aortic v...
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Chapter
Coronary Artery Disease
Anomalous origin of the left coronary artery from the pulmonary trunk usually presents in early infancy with congestive cardiac failure due to ischemic myocardial dysfunction. The diagnosis can usually be made...
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Chapter
Dilated Cardiomyopathy
Dilated cardiomyopathy is characterized by left ventricular dilatation, increased end diastolic volume, and reduced systolic function (typically ejection fraction less than 40%) [1, 2].
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Chapter
Aortic Valve
The aortic valve is a passive valve made up of three leaflets which assume the shape of half moons (semi-lunar). Opposite to the mitral valve, there is no true aortic fibrous annulus but a complex root made up...
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Article
Open AccessPrognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy using cardiovascular magnetic resonance
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Article
Guidelines for autopsy investigation of sudden cardiac death
Although sudden cardiac death is one of the most important mode of death in Western Countries, pathologists and public health physicians have not given this problem the attention it deserves. New methods of pr...
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Book
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Article
Detection of enterovirus capsid protein VP1 in myocardium from cases of myocarditis or dilated cardiomyopathy by immunohistochemistry: further evidence of enterovirus persistence in myocytes
The association of enteroviruses with myocardial disease has been investigated extensively by molecular biological techniques to detect viral RNA, but remains controversial. This retrospective study investigat...