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  1. No Access

    Article

    Dataset for the reporting of neoplasms of the heart, pericardium, and great vessels: recommendations from the International Collaboration on Cancer Reporting (ICCR)

    The International Collaboration on Cancer Reporting (ICCR) was founded by major pathology organizations from around the world to produce internationally standardized and evidence-based datasets for pathologis...

    Joseph J. Maleszewski, Cristina Basso, Allen Burke, Mathieu Castonguay in Virchows Archiv (2023)

  2. Article

    Open Access

    Post-mortem study of the association between cardiac iron and fibrosis in transfusion dependent anaemia

    Heart failure related to cardiac siderosis remains a major cause of death in transfusion dependent anaemias. Replacement fibrosis has been reported as causative of heart failure in siderotic cardiomyopathy in ...

    Paul Kirk, Mary Sheppard in Journal of Cardiovascular Magnetic Resonan… (2017)

  3. Article

    Open Access

    Non-invasive assessment of interstitial myocardial fibrosis in pressure-overload left ventricular hypertrophy

    Andrew Jabbour, Tevfik F Ismail in Journal of Cardiovascular Magnetic Resonan… (2012)

  4. No Access

    Chapter

    Restrictive Cardiomyopathy

    Restrictive cardiomyopathy is a condition characterized by normal left ventricular cavity size and systolic function but with increased myocardial stiffness [1]. This makes the ventricle incompliant and fill p...

    Michael Y. Henein, Mary Sheppard in Clinical Echocardiography (2012)

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    Chapter

    Diseases of the Aorta

    Acute aortic dissection is a surgical emergency that requires accurate diagnosis and prompt management. A number of classifications exist, the simplest of which classifies aortic dissection according to the lo...

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

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    Chapter

    Pericardial Disease

    The pericardium consists of two layers, a visceral layer lined by mesothelial cells and a parietal or fibrous layer lined also by mesothelial cells but with attached fat and fibrous tissue. The mesothelial lay...

    Michael Y. Henein, Mary Sheppard in Clinical Echocardiography (2012)

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    Chapter

    Tricuspid Valve

    The morphologically right atrioventricular valve has three leaflets (tricuspid): septal, inferior (mural), and anterosuperior which are separated from each other by anteroseptal, superoinferior, and inferosept...

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

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    Chapter

    Valve Substitutes

    For the last 40 years, valve replacement with various substitutes in patients with severe valve dysfunction has been practiced, particularly in those with unrepairable valve deformation [1].

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

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    Chapter

    Hypertrophic Cardiomyopathy

    Hypertrophic cardiomyopathy (HCM) is a primary cardiac muscle disorder with unique pathophysiology, heterogeneous expression, and diverse clinical presentations. It is probably the most common genetically tran...

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

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    Chapter

    Pulmonary Hypertension

    Pulmonary hypertension describes raised pulmonary circulatory pressure, venous or arterial. Venous pulmonary hypertension is more common in daily practice than primary arterial hypertension.

    Michael Y. Henein, Mary Sheppard in Clinical Echocardiography (2012)

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    Chapter

    Cardiac Tumors

    Cardiac tumors are rarely suspected clinically but usually appear as unexpected findings when patients are investigated for syncope, breathlessness, thromboembolism, or constitutional manifestations such as co...

    Michael Y. Henein, Mary Sheppard, Michael Rigby in Clinical Echocardiography (2012)

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    Chapter

    Pulmonary Valve

    The pulmonary valve lies anterior and to the left of the aortic valve. The three pulmonary leaflets assume the shape of half moons (semi-lunar) and are similar but usually not equal in size. The right and left...

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

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    Chapter

    Mitral Valve

    The mitral valve is composed of two leaflets, an annulus, chordae tendineae, and two papillary muscles. The anterior (aortic) leaflet is attached to the root of the aorta in direct continuity with the aortic v...

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

  14. No Access

    Chapter

    Coronary Artery Disease

    Anomalous origin of the left coronary artery from the pulmonary trunk usually presents in early infancy with congestive cardiac failure due to ischemic myocardial dysfunction. The diagnosis can usually be made...

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

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    Chapter

    Dilated Cardiomyopathy

    Dilated cardiomyopathy is characterized by left ventricular dilatation, increased end diastolic volume, and reduced systolic function (typically ejection fraction less than 40%) [1, 2].

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

  16. No Access

    Chapter

    Aortic Valve

    The aortic valve is a passive valve made up of three leaflets which assume the shape of half moons (semi-lunar). Opposite to the mitral valve, there is no true aortic fibrous annulus but a complex root made up...

    Michael Y. Henein, Mary Sheppard, John R. Pepper in Clinical Echocardiography (2012)

  17. Article

    Open Access

    Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy using cardiovascular magnetic resonance

    Rory O'Hanlon, Agata Grasso in Journal of Cardiovascular Magnetic Resonan… (2010)

  18. No Access

    Article

    Guidelines for autopsy investigation of sudden cardiac death

    Although sudden cardiac death is one of the most important mode of death in Western Countries, pathologists and public health physicians have not given this problem the attention it deserves. New methods of pr...

    Cristina Basso, Margaret Burke, Paul Fornes, Patrick J Gallagher in Virchows Archiv (2008)

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    Book

  20. Article

    Detection of enterovirus capsid protein VP1 in myocardium from cases of myocarditis or dilated cardiomyopathy by immunohistochemistry: further evidence of enterovirus persistence in myocytes

    The association of enteroviruses with myocardial disease has been investigated extensively by molecular biological techniques to detect viral RNA, but remains controversial. This retrospective study investigat...

    Hongyi Zhang, Yanwen Li, Dougal R. McClean in Medical Microbiology and Immunology (2004)

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