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  1. Article

    Open Access

    Adjusted Indirect Treatment Comparison of Progression-Free Survival with D-Rd and VRd Based on MAIA and SWOG S0777 Individual Patient-Level Data

    Daratumumab plus lenalidomide and dexamethasone (D-Rd) and bortezomib plus lenalidomide and dexamethasone (VRd) are commonly used treatment combinations for transplant-ineligible (TIE) patients with newly diag...

    Brian G. M. Durie, Shaji K. Kumar, Eric M. Ammann, Alex Z. Fu in Advances in Therapy (2024)

  2. Article

    Author Correction: Prevalence of smoldering multiple myeloma based on nationwide screening

    Sigrún Thorsteinsdóttir, Gauti K. Gíslason, Thor Aspelund in Nature Medicine (2023)

  3. Article

    Open Access

    Determining hemodilution in diagnostic bone marrow aspirated samples in plasma cell disorders by next-generation flow cytometry: Proposal for a bone marrow quality index

    Hemodilution of bone marrow (BM) aspirates is a limitation of multiparameter flow cytometry (MFC) in plasma cell disorders. There is a need for a validated approach for assessing sample quality and the distrib...

    Jón Þórir Óskarsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir in Blood Cancer Journal (2023)

  4. Article

    Open Access

    Correction: Iceland screens, treats, or prevents multiple myeloma (iStopMM): a population-based screening study for monoclonal gammopathy of undetermined significance and randomized controlled trial of follow-up strategies

    Sæmundur Rögnvaldsson, Thorvardur Jon Love, Sigrun Thorsteinsdottir in Blood Cancer Journal (2023)

  5. No Access

    Article

    Prevalence of smoldering multiple myeloma based on nationwide screening

    Smoldering multiple myeloma (SMM) is an asymptomatic precursor to multiple myeloma. Here we define the epidemiological characteristics of SMM in the general population in Iceland. The iStopMM study (ClinicalTr...

    Sigrún Thorsteinsdóttir, Gauti K. Gíslason, Thor Aspelund in Nature Medicine (2023)

  6. Article

    Open Access

    Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: Results of the iStopMM study

    Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic...

    Thorir Einarsson Long, Olafur Skuli Indridason, Runolfur Palsson in Blood Cancer Journal (2022)

  7. Article

    Open Access

    Monoclonal gammopathy of undetermined significance and COVID-19: a population-based cohort study

    Multiple myeloma (MM) patients have increased risk of severe coronavirus disease 2019 (COVID-19) when infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Monoclonal gammopathy of undeterm...

    Saemundur Rognvaldsson, Elias Eythorsson, Sigrun Thorsteinsdottir in Blood Cancer Journal (2021)

  8. Article

    Open Access

    Treatment patterns and outcomes in elderly patients with newly diagnosed multiple myeloma: results from the Connect® MM Registry

    Hans C. Lee, Sikander Ailawadhi, Cristina J. Gasparetto in Blood Cancer Journal (2021)

  9. Article

    Open Access

    Iceland screens, treats, or prevents multiple myeloma (iStopMM): a population-based screening study for monoclonal gammopathy of undetermined significance and randomized controlled trial of follow-up strategies

    Monoclonal gammopathy of undetermined significance (MGUS) precedes multiple myeloma (MM). Population-based screening for MGUS could identify candidates for early treatment in MM. Here we describe the Iceland S...

    Sæmundur Rögnvaldsson, Thorvardur Jon Love, Sigrun Thorsteinsdottir in Blood Cancer Journal (2021)

  10. Article

    Open Access

    International Myeloma Working Group risk stratification model for smoldering multiple myeloma (SMM)

    Smoldering multiple myeloma (SMM) is an asymptomatic precursor state of multiple myeloma (MM). Recently, MM was redefined to include biomarkers predicting a high risk of progression from SMM, thus necessitatin...

    María-Victoria Mateos, Shaji Kumar, Meletios A. Dimopoulos in Blood Cancer Journal (2020)

  11. Article

    Open Access

    Longer term follow-up of the randomized phase III trial SWOG S0777: bortezomib, lenalidomide and dexamethasone vs. lenalidomide and dexamethasone in patients (Pts) with previously untreated multiple myeloma without an intent for immediate autologous stem cell transplant (ASCT)

    SWOG S0777, a randomized phase III trial, compared bortezomib, lenalidomide and dexamethasone (VRd) with lenalidomide and dexamethasone (Rd). This updated analysis includes 460 patients evaluable for survival ...

    Brian G. M. Durie, Antje Hoering, Rachael Sexton, Muneer H. Abidi in Blood Cancer Journal (2020)

  12. Article

    Open Access

    Impact of post-transplantation maintenance therapy on health-related quality of life in patients with multiple myeloma: data from the Connect® MM Registry

    Maintenance therapy after autologous stem cell transplantation (ASCT) is recommended for use in multiple myeloma (MM); however, more data are needed on its impact on health-related quality of life (HRQoL). Pre...

    Rafat Abonour, Lynne Wagner, Brian G.M. Durie, Sundar Jagannath in Annals of Hematology (2018)

  13. Article

    Open Access

    Clinical predictors of long-term survival in newly diagnosed transplant eligible multiple myeloma — an IMWG Research Project

    Purpose: multiple myeloma is considered an incurable hematologic cancer but a subset of patients can achieve long-term remissions and survival. The present study examines the clinical features of long-term sur...

    Saad Z. Usmani, Antje Hoering, Michele Cavo, Jesus San Miguel in Blood Cancer Journal (2018)

  14. Article

    Open Access

    Recommendations for acquisition, interpretation and reporting of whole body low dose CT in patients with multiple myeloma and other plasma cell disorders: a report of the IMWG Bone Working Group

    Whole Body Low Dose CT (WBLDCT) has important advantages as a first-line imaging modality for bone disease assessment in patients with plasma cell disorders and has been included in the 2014 International Myel...

    Lia A. Moulopoulos, Vassilis Koutoulidis, Jens Hillengass in Blood Cancer Journal (2018)

  15. No Access

    Article

    Observational study of multiple myeloma in Latin America

    Relatively little is known about the outcomes of multiple myeloma in Latin America, a world region where incorporation of novel agents is generally slow. In the current retrospective-prospective study, we aime...

    Vania T. M. Hungria, Angelo Maiolino, Gracia Martinez in Annals of Hematology (2017)

  16. No Access

    Article

    Awareness, concern, and communication between physicians and patients on bone health in cancer

    This study aims to explore physician–patient communications about bone metastases and cancer treatment-induced bone loss (CTIBL).

    Debu Tripathy, Brian G. M. Durie, Beatrice Mautner in Supportive Care in Cancer (2014)

  17. No Access

    Chapter

    The Role of Anatomic and Functional Imaging in Myeloma

    Brian G.M. Durie in Myeloma Therapy (2008)

  18. No Access

    Article

    Phase II evaluation of bisantrene in refractory multiple myeloma

    Brian G. M. Durie, John Crowley, Charles A. Coltman Jr. in Investigational New Drugs (1991)

  19. No Access

    Chapter

    Workshop on growth factors

    The ‘Workshop on Growth Factors’ which took place at the Lugano Lymphoma Conference on June 8, 1990, included a presentation by Michael Sporn on the concept that loss of inhibitory control mechanisms may be im...

    Professor Derek Crowther, Michael B. Sporn, Anita B. Roberts in Annals of Oncology (1991)

  20. No Access

    Chapter and Conference Paper

    Cytogenetic Abnormalities in Multiple Myeloma

    Cytogenic studies in multiple myeloma have been very difficult because of the predominantly low proliferative activity in this disease (1-7). In the series reported to date the most commonly affected chromosomes ...

    Brian G. M. Durie, Elizabeth E. Vela in Epidemiology and Biology of Multiple Myelo… (1991)

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