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Article
Open AccessThe STOP Program: a Hybrid Smoking Prevention and Cessation Training for Cancer Care Providers in Colombia and Peru
We designed and tested the feasibility of the Smoking Cessation Training Program for Oncology Practice (STOP), a hybrid (face-to-face plus web-based) educational intervention to enhance Spanish-speaking cancer...
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Article
Author Correction: Supporting US public health experts
A Correction to this paper has been published: https://doi.org/10.1038/s41587-020-00792-5.
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Article
Supporting US public health experts
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Article
Percutaneous thermal ablation for treatment of osteoid osteoma: a systematic review and analysis
Although radiofrequency ablation is well validated for treatment of osteoid osteoma, newer technologies, namely cryoablation, have been less thoroughly studied. The purpose is to perform a systematic review an...
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Article
Mindfulness, Conflict Strategy Use, and Relational Satisfaction: a Dyadic Investigation
Research suggests that the capacity to be mindful is positively associated with constructive conflict strategy use and negatively associated with destructive conflict strategy use when individuals experience d...
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Article
Open AccessDisease and outcome disparities in multiple myeloma: exploring the role of race/ethnicity in the Cooperative Group clinical trials
Multiple myeloma (MM) is an incurable hematologic malignancy with disparities in outcomes noted among racial-ethnic subgroups, likely due to disparities in access to effective treatment modalities. Clinical tr...
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Book
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Chapter
Optimal Three-Group Splits Based on a Survival Outcome
In clinical research it is often desirable to discretize a continuous or ordered covariate. In this paper, we investigate the use of various running ordered logrank tests for finding optimal 3-group splits bas...
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Chapter
Cure-Rate Survival Models and Their Application to Cancer Clinical Trials
Many patients with cancer can be of their disease and cure models can be a useful tool to analyze and describe cancer clinical trial survival data. This goal of this chapter is to: (i) review what a cure mod...
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Chapter
The Probability of Being in Response Function and Its Applications
Cancer clinical trials usually have two or more types of related clinical events (i.e. response, progression and relapse). Hence, to compare treatments, efficacy is often measured using composite endpoints. Te...
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Chapter
An Evaluation of Gene Set Analysis for Biomarker Discovery with Applications to Myeloma Research
In this paper, we evaluate 15 methods for gene set analysis in problems. We employ four datasets from myeloma research and three types of biological gene sets, encompassing a total of 12 scenarios. Taking ...
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Article
Open AccessRemoving batch effects from purified plasma cell gene expression microarrays with modified ComBat
Gene expression profiling (GEP) via microarray analysis is a widely used tool for assessing risk and other patient diagnostics in clinical settings. However, non-biological factors such as systematic changes i...
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Article
The Automatic Clinical Trial: Leveraging the Electronic Medical Record in Multisite Cancer Clinical Trials
Submission of data into clinical trial electronic data capture (EDC) systems currently requires redundant entry of data that already exist in the electronic medical record (EMR). Being able to automatically tr...
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Article
Quality improvement guidelines for pediatric abscess and fluid drainage
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Article
Prognostic factor analyses of myeloma survival with intergroup trial S9321 (INT 0141): examining whether different variables govern different time segments of survival
Multiple myeloma (MM) survival plots usually display steeper initial and shallower subsequent slopes reflecting differences in disease biology and likely prognostic factors (PF). S9321 trial was selected to de...
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Article
Apoptosis: a clinical perspective
Dissection of the signalling pathways mediating apoptosis — controlled cell death — in cancer, inflammation and neurodegenerative disorders has stimulated the discovery of a wealth of potential drugs to target...
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Article
Open AccessGenomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival
We have engaged in an international program designated the Bank On A Cure, which has established DNA banks from multiple cooperative and institutional clinical trials, and a platform for examining the association...
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Chapter and Conference Paper
CGMP Manufacturing of a Fusion Protein in Mammalian Cells Using a Large-Scale Acoustic Perfusion System
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Chapter
From Luxury to Comfort and Back Again: Landscape Architecture and the Cottage in Britain and America
In Sense and Sensibility the egregious Robert Ferrars expressed his envy for the new cottage life of the Miss Dashwoods:
I am excessively fond of a cottage; there is always so much comfort, so muc...
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Article
Monitoring a recombinant Pichia pastoris fed batch process using Fourier transform mid-infrared spectroscopy (FT-MIRS)
The use of Fourier transform mid-infrared spectroscopy (FT-MIRS) to predict the concentrations of key analytes in fed-batch cultivations of an industrial strain of Pichia pastoris in a chemical complex medium was...
