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Open AccessTriple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
Retatrutide is a novel triple agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1 and glucagon receptors. A 48-week phase 2 obesity study demonstrated weight reductions of 22.8...
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Open AccessThe effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity
To evaluate whether the association between plasma branched-chain amino acids (BCAA) and intrahepatic lipid (IHL) was affected by physical activity level. Furthermore, to investigate if a conventional exercise...
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Open AccessEffects of exercise training on intrahepatic lipid content in humans
Non-alcoholic fatty liver (NAFL) is the most common liver disorder in western society. Various factors may play a role in determining hepatic fat content, such as delivery of lipids to the liver, de novo lipog...
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PS3 - 14. The effect of the exercise-induced muscle secretome on liver gene expression
Physical exercise training is perhaps the single most effective intervention to both prevent and treat insulin resistance and type 2 diabetes. Accumulating evidence now suggests that the liver plays an importa...
