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Article
Applying polyvinyl alcohol to the preparation of various nanoparticles
Providing nanoscale monodisperse particles in nanoparticle-based drug delivery systems (DDSs) is an important issue in particle synthesis. To prepare uniform, controlled nanoparticles, the addition of stabiliz...
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Article
Safety of applying influenza-antigen-coated microneedles to rat skin and the antigen specific immune response in vivo
Technological advancements and innovations in the use of microneedles for medicinal purposes are constantly emerging. To promote the marketing of microneedles, the safety of microneedle systems during applicat...
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Article
Considerations related to the in-use stability of sterile pharmaceutical dosage forms
It is essential to ensure the in-use stability of sterile preparations because they may be vulnerable to microbial contamination during the opening and preparation process. Although some regulatory agencies pr...
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Article
An economically advantageous amorphous solid dispersion of the fixed combination of lopinavir and ritonavir
Solid dispersion strategies have recently been used to increase the solubility and bioavailability of poorly soluble drugs. Among these various strategies for solid dispersion, the method using polymers and ad...
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Article
Open AccessMigration and invasion of drug-resistant lung adenocarcinoma cells are dependent on mitochondrial activity
A small proportion of cancer cells have stem-cell-like properties, are resistant to standard therapy and are associated with a poor prognosis. The metabolism of such drug-resistant cells differs from that of n...
