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Article
A genetics-led approach defines the drug target landscape of 30 immune-related traits
Most candidate drugs currently fail later-stage clinical trials, largely due to poor prediction of efficacy on early target selection1. Drug targets with genetic support are more likely to be therapeutically vali...
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Article
Open AccessXGR software for enhanced interpretation of genomic summary data, illustrated by application to immunological traits
Biological interpretation of genomic summary data such as those resulting from genome-wide association studies (GWAS) and expression quantitative trait loci (eQTL) studies is one of the major bottlenecks in me...