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Open AccessAuthor Correction: Development of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers
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Open AccessDevelopment of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers
Alzheimer’s disease (AD) and related tauopathies are associated with pathological tau protein aggregation, which plays an important role in neurofibrillary degeneration and dementia. Targeted immunotherapy to ...
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Article
Open AccessA randomized controlled trial of postoperative rehabilitation using digital healthcare system after rotator cuff repair
A digital healthcare system based on augmented reality (AR) has promising uses for postoperative rehabilitation. We compare effectiveness of AR-based and conventional rehabilitation in patients after rotator c...
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Article
Mepirapim, a novel synthetic cannabinoid, induces Parkinson’s disease-related behaviors by causing maladaptation of the dopamine system in the brain
Mepirapim is a novel synthetic cannabinoid that first appeared on the illicit drug market in 2013. In recent years, recreational abuse of Mepirapim has caused serious emergencies, posing a threat to public hea...
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Article
Open AccessIdentification and validation of methylated PENK gene for early detection of bladder cancer using urine DNA
Early detection of bladder cancer (BCa) offers patients a favorable outcome and avoids the need for cystectomy. Development of an accurate and sensitive noninvasive BCa diagnostic test is imperative. DNA methy...
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Oculomics for sarcopenia prediction: a machine learning approach toward predictive, preventive, and personalized medicine
Sarcopenia is characterized by a gradual loss of skeletal muscle mass and strength with increased adverse outcomes. Recently, large-scale epidemiological studies have demonstrated a relationship between severa...
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Article
Correction to: New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents
Unfortunately, original publication of the article has been published with an error in author contribution. The following phrase is added for correction.
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Article
New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents
2C (2C-x) is the general name for the family of phenethylamines containing two methoxy groups at the 2 and 5 positions of the benzene ring. The abuse of 2C family drugs has grown rapidly, although the abuse po...
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25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodents
The use of new psychoactive substances (NPSs) as a substitute for illegal drugs is increasing rapidly and is a serious threat to public health. 25C-NBF is a newly synthesized phenethylamine-type NPS that acts ...
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Open AccessGenipin induces mitochondrial dysfunction and apoptosis via downregulation of Stat3/mcl-1 pathway in gastric cancer
Genipin is a compound derived from gardenia fruit extract. Although Genipin has anti-tumor effects in various cancers, its effect and mechanism in gastric cancer remain unclear. Here, we investigated the relat...
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Open AccessDual modulation of human hepatic zonation via canonical and non-canonical Wnt pathways
The hepatic lobule is divided into three zones along the portal-central vein axis. Hepatocytes within each zone exhibit a distinctive gene expression profile that coordinates their metabolic compartmentalizati...
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Open AccessAlveolar macrophages modulate allergic inflammation in a murine model of asthma
The role of alveolar macrophages (AMs) in the pathogenesis of asthma is still unknown. The aim of the present study was to investigate the effects of AM in the murine model of asthma. AMs were selectively depl...