31 Result(s)
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Bo-Ram **
Biomedicine
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Article
Open AccessAuthor Correction: Development of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers
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Open AccessDevelopment of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers
Alzheimer’s disease (AD) and related tauopathies are associated with pathological tau protein aggregation, which plays an important role in neurofibrillary degeneration and dementia. Targeted immunotherapy to ...
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Mepirapim, a novel synthetic cannabinoid, induces Parkinson’s disease-related behaviors by causing maladaptation of the dopamine system in the brain
Mepirapim is a novel synthetic cannabinoid that first appeared on the illicit drug market in 2013. In recent years, recreational abuse of Mepirapim has caused serious emergencies, posing a threat to public hea...
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Open AccessPatient-derived cell-based pharmacogenomic assessment to unveil underlying resistance mechanisms and novel therapeutics for advanced lung cancer
A pharmacogenomic platform using patient-derived cells (PDCs) was established to identify the underlying resistance mechanisms and tailored treatment for patients with advanced or refractory lung cancer.
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Open AccessIdentification and validation of methylated PENK gene for early detection of bladder cancer using urine DNA
Early detection of bladder cancer (BCa) offers patients a favorable outcome and avoids the need for cystectomy. Development of an accurate and sensitive noninvasive BCa diagnostic test is imperative. DNA methy...
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Oculomics for sarcopenia prediction: a machine learning approach toward predictive, preventive, and personalized medicine
Sarcopenia is characterized by a gradual loss of skeletal muscle mass and strength with increased adverse outcomes. Recently, large-scale epidemiological studies have demonstrated a relationship between severa...
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Control of a nosocomial measles outbreak among previously vaccinated adults in a population with high vaccine coverage: Korea, 2019
We describe a measles outbreak among previously vaccinated healthcare workers (HCWs) and inpatients and the control measures implemented at a tertiary care hospital in 2019. Case-patients were laboratory-confi...
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Open AccessVibrio vulnificus induces the death of a major bacterial species in the mouse gut via cyclo-Phe-Pro
A foodborne pathogen, Vibrio vulnificus, encounters normal microflora inhabiting the gut environments prior to causing fatal septicemia or gastroenteritis and should overcome the barriers derived from the gut com...
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Open AccessReal-time PCR biochip for on-site detection of Coxiella burnetii in ticks
Q fever, a zoonosis caused by Coxiella burnetii, has adverse effects on public health. Ticks are vectors of C. burnetii and they contribute to the transmission of the pathogen. A tool for rapid, sensitive, and ac...
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Correction to: New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents
Unfortunately, original publication of the article has been published with an error in author contribution. The following phrase is added for correction.
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New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents
2C (2C-x) is the general name for the family of phenethylamines containing two methoxy groups at the 2 and 5 positions of the benzene ring. The abuse of 2C family drugs has grown rapidly, although the abuse po...
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Effect of nifedipine, a calcium channel blocker, on the generation of nitric oxide and interleukin-1β by murine macrophages activated by lipopolysaccharide from Prevotella intermedia
Nifedipine, a calcium channel blocker, has been reported to possess anti-inflammatory and immunosuppressive effects. The current study was undertaken to explore the influence of nifedipine on the generation of...
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Correction to: Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats
The authors have noted an error in Fig. 1B and Fig. 1C.
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Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats
Drug use during adolescence results in a lifelong risk to develop substance-use disorders. Adolescent rats are less reactive to cocaine-associated cues compared with adults; however, the contribution of adoles...
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25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodents
The use of new psychoactive substances (NPSs) as a substitute for illegal drugs is increasing rapidly and is a serious threat to public health. 25C-NBF is a newly synthesized phenethylamine-type NPS that acts ...
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Prediction of Ankle Brachial Index with Photoplethysmography Using Convolutional Long Short Term Memory
Early detection is critical for effective prevention of cardiovascular disease. One of the representative indicators of cardiovascular disease is the ankle-brachial index (ABI). It is mainly used to measure ar...
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Open AccessGenipin induces mitochondrial dysfunction and apoptosis via downregulation of Stat3/mcl-1 pathway in gastric cancer
Genipin is a compound derived from gardenia fruit extract. Although Genipin has anti-tumor effects in various cancers, its effect and mechanism in gastric cancer remain unclear. Here, we investigated the relat...
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Open AccessCross-talk between ER stress and mitochondrial pathway mediated adriamycin-induced testicular toxicity and DA-9401 modulate adriamycin-induced apoptosis in Sprague–Dawley rats
DA-9401 was prepared as a mixture of Chinese medicinal herb extracts from roots of Morinda officinalis How (Rubiaceae), outer scales of Allium cepa L. (Liliceae) and seeds of Cuscuta chinensis Lamark (Convolvulac...
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Open AccessLymphatic endothelial cells promote productive and latent HIV infection in resting CD4+ T cells
An HIV cure has not yet been achieved because latent viral reservoirs persist, particularly in resting CD4+ T lymphocytes. In vitro, it is difficult to infect resting CD4+ T cells with HIV-1, but infections readi...
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Tablet Formulation of a Polymeric Solid Dispersion Containing Amorphous Alkalinized Telmisartan
To overcome the poor dissolution of telmisartan (TMS) at weak acidic pH, amorphous alkalinized TMS (AAT) was prepared by introducing sodium hydroxide as a selective alkalizer. AAT-containing polymeric solid di...
