10 Result(s)
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BingLiang Fang
Biomedicine
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Article
Open AccessAuthor Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
A Correction to this paper has been published: https://doi.org/10.1038/s41588-021-00811-4.
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Article
Open AccessConservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Patient-derived xenografts (PDXs) are resected human tumors engrafted into mice for preclinical studies and therapeutic testing. It has been proposed that the mouse host affects tumor evolution during PDX engr...
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Article
Open AccessRepurposing auranofin to treat TP53-mutated or PTEN-deleted refractory B-cell lymphoma
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Open AccessPatient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer
Because patient-derived xenografts (PDXs) are grown in immunodeficient mouse strains, PDXs are regarded as lacking an immune microenvironment. However, whether patients’ immune cells co-exist in PDXs remains u...
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Article
Open AccessImmunotherapy for non-small cell lung cancers: biomarkers for predicting responses and strategies to overcome resistance
Recent breakthroughs in targeted therapy and immunotherapy have revolutionized the treatment of lung cancer, the leading cause of cancer-related deaths in the United States and worldwide. Here we provide an ov...
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Author Correction: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer
In the version of this article originally published, information regarding several funding sources was omitted from the Acknowledgements section. The following sentences should have been included: “This work w...
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Article
Open AccessPredictive biomarkers in precision medicine and drug development against lung cancer
The molecular characterization of various cancers has shown that cancers with the same origins, histopathologic diagnoses, and clinical stages can be highly heterogeneous in their genetic and epigenetic altera...
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Open AccessElafin, an inhibitor of elastase, is a prognostic indicator in breast cancer
Elafin is an elastase-specific inhibitor with increased transcription in normal mammary epithelial cells compared to mammary carcinoma cells. In this report, we test the hypothesis that inhibition of elastase,...
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Open AccessTargeting different types of human meningioma and glioma cells using a novel adenoviral vector expressing GFP-TRAIL fusion protein from hTERT promoter
The objective of this study was to evaluate the anti-tumor effects of Ad/gTRAIL (an adenoviral vector in which expression of GFP and TRAIL is driven by a human telomerase reverse transcriptase promoter, hTERT)...
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Open AccessOxidative stress in NSC-741909-induced apoptosis of cancer cells
NSC-741909 is a novel anticancer agent that can effectively suppress the growth of several cell lines derived from lung, colon, breast, ovarian, and kidney cancers. We recently showed that NSC-741909-induced a...
