-
Article
Open AccessDevelopment and validation of a novel prognostic nomogram for advanced diffuse large B cell lymphoma
Advanced diffuse large B cell lymphoma (DLBCL) is a common malignant tumor with aggressive clinical features and poor prognosis. At present, there is lack of effective prognostic tool for patients with advance...
-
Article
Open AccessThe clinical and genomic distinctions of Class1/2/3 BRAF-mutant colorectal cancer and differential prognoses
BRAF mutations are the oncogenic drivers in colorectal cancer and V600 mutations (Class1), which lead to RAS-independent active monomers, are the most common mutation types. BRAF non-V600 mutants can be further ...
-
Article
Open AccessClinical features and treatment outcome of lymphoepithelioma-like carcinoma from multiple primary sites: a population-based, multicentre, real-world study
Lymphoepithelioma-like carcinoma (LELC) is a rare and unique subtype of cancer that histologically resembles undifferentiated nasopharyngeal carcinoma (NPC). The population-based analysis of LELC and the optim...
-
Article
Open AccessPatient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer
Because patient-derived xenografts (PDXs) are grown in immunodeficient mouse strains, PDXs are regarded as lacking an immune microenvironment. However, whether patients’ immune cells co-exist in PDXs remains u...
