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  1. No Access

    Article

    Synthesis, biological activities studies of ruthenium(II) polypyridyl complexes

    Four ruthenium(II) polypyridyl complexes were synthesized and characterized by elemental analysis, IR, ESI-MS and 1H NMR. The in vitro cytotoxicities of the complexes against BEL-7402, HeLa, A549, HepG2 and MG-63...

    Bing Tang, Bing-Jie Han, Dan Wan, Shang-Hai Lai… in Transition Metal Chemistry (2017)

  2. No Access

    Article

    DNA-Binding, Photocleavage, and Photodynamic Anti-cancer Activities of Pyridyl Corroles

    The DNA-binding, photocleavage, and antitumor activity of three free base pyridyl corroles 1, 2, and 3 have been investigated. The binding affinity toward CT-DNA decreases with increasing number of pentafluorophe...

    Zhen-Hua Liang, Hai-Yang Liu, Rong Zhou, Zao Zhang… in The Journal of Membrane Biology (2016)

  3. No Access

    Article

    Synthesis, Molecular Structure, DNA/Protein Binding, Cytotoxicity, Apoptosis, Reactive Oxygen Species, and Mitochondrial Membrane Potential of Dibenzoxanthenes Derivatives

    Two dibenzoxanthene isomers 3 and 4 were synthesized and characterized. The crystal structures of the two compounds were solved by single-crystal X-ray diffraction. Binding of two compounds with calf thymus DNA (...

    Hui-Hui Yang, Bing-Jie Han, Wei Li, Yun-Jun Liu… in The Journal of Membrane Biology (2015)

  4. No Access

    Article

    Ruthenium(II) polypyridyl complexes: synthesis, cytotoxicity in vitro, reactive oxygen species, mitochondrial membrane potential and cell cycle arrest studies

    Two Ru(II) polypyridyl complexes [Ru(dmb)2(idpq)](ClO4)2 (1) (idpq = indeno[1,2-b]dipyrido[3,2-f:2′,3′-h]-quinoxaline-6-one, dmb = 4,4′-dimethyl-2,2′-bipyridine) and [Ru(bpy)2(idpq)](ClO4)2 (2) (bpy = 2,2′-bipyr...

    Bing-Jie Han, Guang-Bin Jiang, Ji Wang, Wei Li… in Transition Metal Chemistry (2015)

  5. No Access

    Article

    Apoptosis in BEL-7402 cells induced by ruthenium(II) complexes through a ROS-mediated mitochondrial pathway

    Three Ru(II) polypyridyl complexes [Ru(dmb)2(HMSPIP)](ClO4)2 (1), [Ru(phen)2(HMSPIP)](ClO4)2 (2) and [Ru(dmp)2(HMSPIP)](ClO4)2 (3) were synthesized and characterized. The cytotoxicity in vitro, apoptosis, cell cy...

    Guang-Bin Jiang, Wei Li, Ji Wang, Bing-Jie Han, Gan-Jian Lin… in Transition Metal Chemistry (2014)