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Article
Complete genomic characterization of two European-genotype porcine reproductive and respiratory syndrome virus isolates in Fujian province of China
Porcine reproductive and respiratory syndrome (PRRS) is considered one of the most devastating swine diseases worldwide, resulting in immense economic losses. PRRS virus (PRRSV) is divided into two major genot...
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Article
Molecular characterization of two recombinant potato virus Y isolates from China
Isolates of potato virus Y (PVY) have been divided into several strains. We determined the genomic sequences of PVY isolates AQ4 and FZ10 from tobacco in China. AQ4 and FZ10 had genome of 9700 and 9698 nucleot...
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Article
Randomized controlled trial of screening for hepatocellular carcinoma
Screening for hepatocellular carcinoma (HCC) has been conducted for over 20 years, but there is no conclusive evidence that screening may reduce HCC mortality. The aim of this study was to assess the effect o...
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Article
Comparison between radioimmunotherapy and external beam radiation therapy for patients with hepatocellular carcinoma
It has previously been observed in animal studies that, at equivalent doses, radioimmunotherapy (RIT) is 2.5 times more effective than multiple fractions of external beam radiation therapy (EBRT) in inhibitin...
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Article
A possible hydrolysis mechanism of β-naphthyl acetate catalyzed by antibodies
The mechanism of ester hydrolysis has been extensively studied; however, the precise function of active-site residues in promoting catalysis is unclear. We describe here the structural models for the complex o...
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Article
Inhibitory effect of the angiogenesis inhibitor TNP-470 on tumor growth and metastasis in nude mice bearing human hepatocellular carcinoma
The antitumor and anti-metastatic effects of a potent angiogenesis inhibitor,O-(chloroacetyl-carbamoyl)fumagillol (TNP-470), was investigated in a highly metastatic model of human hepatocellular carcinoma—LCI-D20...
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Article
Long-term results of surgery for small primary liver cancer in 514 adults
During 1958–1993, 2030 patients with pathologically proven primary liver cancer (PLC) were retrospectively reviewed. Comparison between small PLC (<-5 cm,n=514) and large PLC (>5 cm,n=1516) revealed that small PL...
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Article
Characteristics and prognosis of primary liver cancer in young patients in China
To investigate the clinicopathologic characteristics of primary liver cancer (PLC) in young adults, 77 patients aged 35 or younger were compared with 603 patients older than 35 years during the same period. In...
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Article
Recurrence after resection ofα-fetoprotein-positive hepatocellular carcinoma
The long-term prognosis of surgery for hepatocellular carcinoma (HCC) is not yet satisfactory, the main reason being the high recurrence rate. The authors report the results of a long-term follow-up of 308 pat...
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Chapter and Conference Paper
Evaluation of Early Detection and Treatment of Hepatocellular Carcinoma
During 1972–1991, 1443 patients with hepatocellular carcinoma (HCC) were studied. Comparison between screening (n=522) and nonscreening (n=921) groups revealed higher small HCC percentage (49.4% vs. 12.4%), hi...
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Chapter
Treatment of hepatocellular carcinoma: A summary of 33 years’ experience
Hepatocellular carcinoma (HCC), the most common type (90-95%) of primary liver cancer (PLC), causes 100,000 deaths every year in China. However, based on various strategies aimed at controlling this neoplasm, ...
