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Article
β-Alanine intercede metabolic recovery for amelioration of human cervical and renal tumors
β-Alanine is a non-essential amino acid and presents as a major component of various sports supplements. It is a non-proteogenic amino acid, formed in vivo by degradation of carnosine, anserine, balenine, and ...
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Article
Toxicological evaluation of aspartame against Madin–Darby canine kidney cells
Aspartame is most widely used as artificial sweeteners in more than 6000 food varieties. Aspartame digested into aspartic acid, phenylalanine, and methanol, and several peroxides, superoxide molecules also gen...
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Article
Synthesis of berberine-piperazine conjugates as potential antioxidant and cytotoxic agents
Piperazine derivatives bearing different electron-withdrawing and electron-donating functional groups were linked to the well-known isoquinoline alkaloid derivative, berberine via efficient organic transformat...
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Article
Time and Concentration-Dependent Therapeutic Potential of Silver Nanoparticles in Cervical Carcinoma Cells
Silver nanoparticles (AgNPs) have well-known anti-bacterial properties and have been widely used in daily life as various medical and general products. There is limited information available on the cytotoxicit...
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Article
Synthesis, antioxidant and anticancer screenings of berberine–indole conjugates
A variety of heterocyclic nitrogen cores in the form of indole moieties were linked to the natural isoquinoline alkaloid molecule berberine to achieve anticipated antioxidant and anticancer properties. An effi...
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Article
Synthesis of piperazine based N-Mannich bases of berberine and their antioxidant and anticancer evaluations
Isoquinoline alkaloids possess versatile biological activities. Hence, in the current research an effort has been made to improve structurally important part of isoquinoline alkaloid berberine because it is re...
