9 Result(s)
within
Benjamin R. Underwood
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Article
Open AccessTemporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019)
Interest in modifiable risk factors (MRFs) for dementia is high, given the personal, social, and economic impact of the disorder, especially in ageing societies such as the United Kingdom. Exploring the popula...
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Open AccessCharacteristics, outcomes, facilitators and barriers for psychosocial interventions on inpatient mental health dementia wards: a systematic review
The National Institute for Health and Care Excellence guidelines state that psychosocial interventions should be the first line of treatment for people with dementia who are experiencing distress behaviours, s...
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Open AccessFood insecurity and subjective cognitive complaints among adults aged ≥ 65 years from low- and middle-income countries
To date, no study has investigated the association between food insecurity and subjective cognitive complaints (SCC). Thus, the aims of the present study were to examine this association among older adults in ...
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Open AccessEating disorders and physical multimorbidity in the English general population
People with eating disorders may be at increased risk for physical health problems, but there are no data on the relationship between eating disorders and physical multimorbidity (i.e., ≥ 2 physical conditions...
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Open AccessPain and mild cognitive impairment among adults aged 50 years and above residing in low- and middle-income countries
Previous studies on the association between pain and cognitive decline or impairment have yielded mixed results, while studies from low- and middle-income countries (LMICs) or specifically on mild cognitive im...
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Open AccessAssociation between cooking fuels and mild cognitive impairment among older adults from six low- and middle-income countries
There is a small body of evidence suggesting that unclean cooking fuel use may be associated with cognitive decline. However, to date, no study has investigated the association between unclean cooking fuel and...
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Article
Dementia with Lewy bodies — from scientific knowledge to clinical insights
Dementia with Lewy bodies (DLB) is the underlying aetiology of 10–15% of all cases of dementia and as such is a clinically important diagnosis. In the past few years, substantial advances have been made in und...
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Open AccessAn open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington’s disease
Preclinical data have shown that rilmenidine can regulate autophagy in models of Huntington’s disease (HD), providing a potential route to alter the disease course in patients. Consequently, a 2-year open-labe...
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Article
Spinocerebellar ataxias caused by polyglutamine expansions: A review of therapeutic strategies
Six of the spinocerebellar ataxias (SCAs) are caused by expanded CAG trinucleotide repeats encoding polyglutamine tracts in different genes. Together with three other neurodegenerative diseases they represent ...
