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Article
Open AccessEnd-of-life care needs in cancer patients: a qualitative study of patient and family experiences
Cancer is a disease that transcends what is purely medical, profoundly affecting the day-to-day life of both patients and family members. Previous research has shown that the consequences of cancer are greatly...
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Article
Open AccessA potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
Parkinson´s disease (PD) is a common neurodegenerative movement disorder and leucine-rich repeat kinase 2 (LRRK2) is a promising therapeutic target for disease intervention. However, the ability to stratify pa...
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Article
Fermentation of D-xylose to Ethanol by Saccharomyces cerevisiae CAT-1 Recombinant Strains
Ethanol production by the D-xylose fermentation of lignocellulosic biomass would augment environmental sustainability by increasing the yield of biofuel obtained per cultivated area. A set of recombinant strai...
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Article
Differential modulation of the bacterial endophytic microbiota of Festuca arundinaceae (tall fescue) cultivars by the plant-growth promoting strain Streptomyces albidoflavus UYFA156
The bacterial endophyte Streptomyces albidoflavus UYFA156 was isolated from seeds of tall fescue, Festuca arundinaceae cultivar SFRO Don Tomás, promoting growth specifically in its host cultivar. Under the hypoth...
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Article
Open AccessIron-induced cytotoxicity mediated by endolysosomal TRPML1 channels is reverted by TFEB
Increased brain iron content has been consistently reported in sporadic Parkinson’s disease (PD) patients, and an increase in cytosolic free iron is known to cause oxidative stress and cell death. However, whe...
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Article
Open AccessMagnetic and Photoluminescent Sensors Based on Metal-Organic Frameworks Built up from 2-aminoisonicotinate
In this work, three isostructural metal-organic frameworks based on first row transition metal ions and 2-aminoisonicotinate (2ain) ligands, namely, {[M(μ-2ain)2]·DMF}n [MII = Co (1), Ni (2), Zn (3)], are evaluat...
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Coupling Syntrophic Acetate Oxidation and Anaerobic Ammonium Oxidation When Treating Nitrogen-Rich Organic Wastes for Energy Recovery and Nitrogen Removal: Overview and Prospects
There is high interest in applying anaerobic digestion to organic wastes for the recovery of biogas as a renewable energy source. In the case of protein-rich residues, the performance of anaerobic digesters mi...
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Article
Open AccessA Potassium Metal-Organic Framework based on Perylene-3,4,9,10-tetracarboxylate as Sensing Layer for Humidity Actuators
We have synthesized a novel three-dimensional metal-organic-framework (MOF) based on the perylene-3,4,9,10-tetracarboxylate linker and potassium as metallic centre. We report the formation of this K-based MOF ...
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Article
Open AccessParkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation
Mutations in LRRK2 are a common genetic cause of Parkinson’s disease (PD). LRRK2 interacts with and phosphorylates a subset of Rab proteins including Rab8a, a protein which has been implicated in various centr...
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Article
Hormonal Profile in Vegetative and Floral Buds of Azalea: Levels of Polyamines, Gibberellins, and Cytokinins
The floral transition includes a complex system of factors that interact and involve various biochemical signals, including plant growth regulators. The physiological signals involved in the control of the flo...
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Article
Clonal micropropagation of six selected half-sibling families of Pinus pinea and somaclonal variation analysis
Organogenesis response of six selected half-sibling families of stone pine (Pinus pinea L.) has been evaluated, showing genotype-dependent behaviour. The caulogenic phase was characterized by high values of Survi...
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Article
Fluorescence resonance energy transfer in ferritin labeled with multiple fluorescent dyes
We simultaneously labeled ferritin with two Alexa Fluor fluorophores (AF350 and AF430). When both fluorophores label the same ferritin subunit, fluorescence resonance energy transfer (FRET) takes place from th...
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Article
Nutritional and gibberellic acid requirements in kiwifruit vitroponic cultures
Residual macronutrients, carbon source, and gibberellic acid (GA3) in the culture medium were measured throughout the whole culture period of kiwi (Actinidia deliciosa Chev. cv. Hayward) explants cultured in liqu...
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Article
Inoculation and nitrate alter phytohormone levels in soybean roots: differences between a supernodulating mutant and the wild type
The levels of different cytokinins, indole-3-acetic acid (IAA) and abscisic acid (ABA) in roots of Glycine max [L.] Merr. cv. Bragg and its supernodulating mutant nts382 were compared for the first time. Forty-e...
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Article
Stomatal and cuticular traits on carnation tissue culture under different ventilation conditions
Establishment of microplants is related to the moisture vapourtransmission of the culture vessel lid. In this respect, stomatal andcuticular physiology were characterized in detached leaves from Dianthuscaryop...
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Article
Endogenous plant growth regulators in carnation tissue cultures under different conditions of ventilation
Endogenous indole-3-acetic acid (IAA), abscisic acid (ABA) and cytokinins (zeatin, zeatin riboside, dihydrozeatin, (diH)Z, dihydrozeatin riboside, (diH)[9R]Z, N6-isopentenyl adenine and N6-isopentenil adenine rib...
