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Article
Open AccessPredicting the potentially exacerbation of severe viral pneumonia in hospital by MuLBSTA score joint CD4 + and CD8 +T cell counts: construction and verification of risk warning model
This study mainly focuses on the immune function and introduces CD4+, CD8+ T cells and their ratios based on the MuLBSTA score, a previous viral pneumonia mortality risk warning model, to construct an early warni...
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Article
Open AccessGlycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro
Inflammation plays a crucial role in the progression of Subacute Ruminal Acidosis (SARA). The experiment was designed to investigate anti-inflammatory effects of glycyrrhizin on goats ruminal epithelial cells ...
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Article
Sensor-based environmental impact of soil erosion in rural areas and rural revitalization in Gansu
Today, sensor technology and microelectromechanical technology, wireless sensor networks have gradually developed as an emerging information acquisition technology. Through the application of wireless sensor n...
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Article
Open AccessSpinal cord injury: molecular mechanisms and therapeutic interventions
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate. The challenges of SCI repair include its complex pathological mechanisms and the difficulties of neural regeneration ...
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Article
Open AccessCombination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation
Spinal cord injury (SCI) causes severe neurological dysfunction and currently has no effective treatment. Due to the complex pathophysiological processes associated with SCI and the limited efficacy of single ...
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Article
Open AccessBiocompatible exosome-modified fibrin gel accelerates the recovery of spinal cord injury by VGF-mediated oligodendrogenesis
Exosomes show potential for treating patients with spinal cord injury (SCI) in clinical practice, but the underlying repair mechanisms remain poorly understood, and biological scaffolds available for clinical ...
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Article
Open AccessIFN-τ mediated miR-26a targeting PTEN to activate PI3K/AKT signalling to alleviate the inflammatory damage of bEECs
Endometritis is the failure of embryo implantation and an important cause of infertility in dairy cows. IFN-τ is a type I interferon unique to ruminants. In regulating the process of inflammatory response, IFN...
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Article
Open AccessA new approach for reducing pollutants level: a longitudinal cohort study of physical exercises in young people
The present study aimed to evaluate the elimination of three common pollutants (dimethoate, benzo(a)pyrene (BaP) and bisphenol A (BPA) by different physical exercises and to assess the possible factors which c...
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Article
Open AccessUrinary levels of dimethoate, bisphenol A and benzo[a]pyrene in first-year students of Hohai University from different geographical regions
The objective of this study was to detect the urinary levels of dimethoate, benzo(a) pyrene (BaP), and bisphenol A (BPA) in first-year Hohai University students with different geographic origins.
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Article
Facet-control in selective area growth (SAG) of a-plane GaN by MOVPE
Selective area growth (SAG) of a-plane GaN grown on r-plane sapphire with a stripe orientation along <1-100> was investigated. The key technology of facet-control is optimizing the growth temperature and the r...
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Article
Open AccessStrain-controlled power devices as inspired by human reflex
Bioinspired electronics are rapidly promoting advances in artificial intelligence. Emerging AI applications, e.g., autopilot and robotics, increasingly spur the development of power devices with new forms. Her...
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Article
Inhibitory effect of estrogen receptor beta on P2X3 receptors during inflammation in rats
Estrogen receptor beta (ERβ) has been shown to play a therapeutic role in inflammatory bowel disease (IBD). However, the mechanism underlying how ERβ exerts therapeutic effects and its relationship with P2X3 r...
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Open AccessInhibition of G protein-coupled P2Y2 receptor induced analgesia in a rat model of trigeminal neuropathic pain
ATP and P2X receptors play important roles in the modulation of trigeminal neuropathic pain, while the role of G protein-coupled P2Y2 receptors and the underlying mechanisms are less clear. The threshold and freq...
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Article
Reply to “Errors in the description of USP certified reference materials”
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3D finite element simulation of explosive welding of three-layer plates
A 3D finite element model of the explosive welding process of three-layer plates with materials of steel-copper-copper is established. Based on the presented model, the bonding mechanism is simulated and analy...
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Article
Estrogen modulation of peripheral pain signal transduction: involvement of P2X3 receptors
There is evidence that gonadal hormones may affect the perception of painful stimulation, although the underlying mechanisms remain unclear. This investigation was undertaken to determine whether the adenosine...
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Article
The US Pharmacopeia: interfacing chemical metrology with pharmaceutical and compendial science
The United States Pharmacopeial Convention (USP) is an official public standards-setting authority for prescription and over-the-counter medicines and other healthcare products manufactured or sold in the Unit...
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Open AccessIncreased 5-HT3-mediated signalling in pelvic afferent neurons from mice deficient in P2X2 and/or P2X3 receptor subunits
Extracellular ATP and 5-hydroxytryptamine (5-HT) are both involved in visceral sensory pathways by interacting with P2X and 5-HT3 receptors, respectively. We have investigated the changes in P2X and 5-HT3-mediate...
