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    Article

    Vsx1 and Chx10 paralogs sequentially secure V2 interneuron identity during spinal cord development

    Paralog factors are usually described as consolidating biological systems by displaying redundant functionality in the same cells. Here, we report that paralogs can also cooperate in distinct cell populations ...

    Stéphanie Debrulle, Charlotte Baudouin in Cellular and Molecular Life Sciences (2020)

  2. Article

    Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and ‘Schizophrenia-Like Behaviors’ in Mice

    Rasd2 is a thyroid hormone target gene, which encodes for a GTP-binding protein enriched in the striatum where, among other functions, it modulates dopaminergic neurotransmission. Here we report that human RASD2 ...

    Daniela Vitucci, Annabella Di Giorgio, Francesco Napolitano in Neuropsychopharmacology (2016)

  3. Article

    Open Access

    Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion

    Mechanisms of gender-specific synaptic plasticity in the striatum, a brain region that controls motor, cognitive and psychiatric functions, remain unclear. Here we report that Rhes, a GTPase enriched in medium sp...

    Veronica Ghiglieri, Francesco Napolitano, Barbara Pelosi in Scientific Reports (2015)