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Article
Open AccessLhx4 surpasses its paralog Lhx3 in promoting the differentiation of spinal V2a interneurons
Paralog factors are considered to ensure the robustness of biological processes by providing redundant activity in cells where they are co-expressed. However, the specific contribution of each factor is freque...
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Article
Vsx1 and Chx10 paralogs sequentially secure V2 interneuron identity during spinal cord development
Paralog factors are usually described as consolidating biological systems by displaying redundant functionality in the same cells. Here, we report that paralogs can also cooperate in distinct cell populations ...
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Article
Open AccessAuthor Correction: Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessOnecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits
In the develo** spinal cord, Onecut transcription factors control the diversification of motor neurons into distinct neuronal subsets by ensuring the maintenance of Isl1 expression during differentiation. Howev...