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  1. Article

    Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and ‘Schizophrenia-Like Behaviors’ in Mice

    Rasd2 is a thyroid hormone target gene, which encodes for a GTP-binding protein enriched in the striatum where, among other functions, it modulates dopaminergic neurotransmission. Here we report that human RASD2 ...

    Daniela Vitucci, Annabella Di Giorgio, Francesco Napolitano in Neuropsychopharmacology (2016)

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    DRD2 genotype predicts prefrontal activity during working memory after stimulation of D2 receptors with bromocriptine

    Pharmacological stimulation of D2 receptors modulates prefrontal neural activity associated with working memory (WM) processing. The T allele of a functional single-nucleotide polymorphism (SNP) within DRD2 (rs10...

    Barbara Gelao, Leonardo Fazio, Pierluigi Selvaggi in Psychopharmacology (2014)

  3. Article

    Treatment with Olanzapine is Associated with Modulation of the Default Mode Network in Patients with Schizophrenia

    Earlier studies have shown widespread alterations of functional connectivity of various brain networks in schizophrenia, including the default mode network (DMN). The DMN has also an important role in the perf...

    Fabio Sambataro, Giuseppe Blasi, Leonardo Fazio, Grazia Caforio in Neuropsychopharmacology (2010)