Skip to main content

and
  1. Article

    Open Access

    Immortalized murine tenocyte cells: a novel and innovative tool for tendon research

    Primary tenocytes rapidly undergo senescence and a phenotypic drift upon in vitro monolayer culture, which limits tendon research. The Ink4a/Arf locus encodes the proteins p16Ink4a/Arf and p14ARF (p19ARF in mice)...

    Gil Lola Oreff, Barbara Maurer, Ahmed N. ELKhamary, Iris Gerner in Scientific Reports (2023)

  2. Article

    Open Access

    Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains

    The transcription factor STAT3 is frequently activated in human solid and hematological malignancies and remains a challenging therapeutic target with no approved drugs to date. Here, we develop synthetic anti...

    Grégory La Sala, Camille Michiels, Tim Kükenshöner in Nature Communications (2020)