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Article
Open AccessPopulation structure and genome-wide evolutionary signatures reveal putative climate-driven habitat change and local adaptation in the large yellow croaker
The large yellow croaker (Larimichthys crocea) is one of the most economically valuable marine fish in China and is a notable species in ecological studies owing to a serious collapse of wild germplasm in the pas...
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Chapter and Conference Paper
LSMD-Net: LiDAR-Stereo Fusion with Mixture Density Network for Depth Sensing
Depth sensing is critical to many computer vision applications but remains challenge to generate accurate dense information with single type sensor. The stereo camera sensor can provide dense depth prediction ...
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Article
Open AccessIdentification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants
Toxin B (TcdB) is a major exotoxin responsible for diseases associated with Clostridioides difficile infection. Its sequence variations among clinical isolates may contribute to the difficulty in develo** effec...
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Article
Open AccessStructure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition
Clostridioides difficile is one of the most common causes of antibiotic-associated diarrhea in developed countries. As key virulence factors of C. difficile, toxin A (TcdA) and toxin B (TcdB) act by glucosylating...
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Article
Open AccessMetabolites profiling and pharmacokinetics of troxipide and its pharmacodynamics in rats with gastric ulcer
Troxipide is widely used to treat gastric ulcer (GU) in the clinic. However, a lack of systematic metabolic, pharmacokinetic and pharmacological studies limits its clinical use. This study aimed to firstly exp...
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Article
Mitogenomic Perspectives on the Adaptation to Extreme Alkaline Environment of Amur ide (Leuciscus waleckii)
Amur ide (Leuciscus waleckii, Family Cyprinidae) is widely distributed in Northeast Asia. L. waleckii usually inhabits freshwater environments but can also survive in the Lake Dali Nur, one of the most extreme aq...
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Article
Construction of a High-Density Genetic Linkage Map and QTL Map** for Growth-Related Traits in Takifugu bimaculatus
Takifugu bimaculatus is a euryhaline species, distributed ranging from the southern Yellow Sea to the South China Sea. Their tolerance to a wide range of salinity and temperature, coupled with a desirable firm te...
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Article
Identification and Characterization of the Two-Component System HK8700–RR8701 of Kocuria rhizophila DC2201
Two-component systems (TCSs) are highly conserved in prokaryotes, endowing cells with multiple physiological functions to respond to changes in the ambient environment. The signaling pathway of a typical TCS c...
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Article
Open AccessThe allotetraploid origin and asymmetrical genome evolution of the common carp Cyprinus carpio
Common carp (Cyprinus carpio) is an allotetraploid species derived from recent whole genome duplication and provides a model to study polyploid genome evolution in vertebrates. Here, we generate three chromosome-...
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Article
Open AccessThe sequencing and de novo assembly of the Larimichthys crocea genome using PacBio and Hi-C technologies
Larimichthys crocea is an endemic marine fish in East Asia that belongs to Sciaenidae in Perciformes. L. crocea has now been recognized as an “iconic” marine fish species in China because not only is it a popular...
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Article
Open AccessThe sequence and de novo assembly of Takifugu bimaculatus genome using PacBio and Hi-C technologies
Takifugu bimaculatus is a native teleost species of the southeast coast of China where it has been cultivated as an important edible fish in the last decade. Genetic breeding programs, which have been recently in...
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Article
Structure of the full-length Clostridium difficile toxin B
Clostridium difficile is an opportunistic pathogen that establishes in the colon when the gut microbiota are disrupted by antibiotics or disease. C. difficile infection (CDI) is largely caused by two virulence fa...
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Article
An off-axis Golay3 sparse aperture telescope with a freeform secondary mirror
The application of freeform surface in an optical system can effectively increase the freedom of optical design and reduce the number of optical elements. In this work, a two-mirror off-axis sparse aperture te...
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Article
Open AccessAn examination of the Northern Hemisphere mid-latitude storm track interannual variability simulated by climate models—sensitivity to model resolution and coupling
The model fidelity in simulating the Northern Hemisphere storm track interannual variability and the connections of this variability to the low frequency atmospheric variations and oceanic variations are exami...
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Article
Genome-Scale Association Study of Abnormal Scale Pattern in Yellow River Carp Identified Previously Known Causative Gene in European Mirror Carp
Common carp (Cyprinus carpio) is one of the most widely studied fish species due to its great economic value and strong environmental adaptability. Scattered scale, a typical phenotype of the mirror carp that is ...
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Article
Population Genomics Reveals Genetic Divergence and Adaptive Differentiation of Chinese Sea Bass (Lateolabrax maculatus)
The marine species usually show high dispersal capabilities accompanied by high levels of gene flow. On the other hand, many physical barriers distribute along the continental marginal seas and may prevent dis...
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Article
Open AccessErratum: An ultra-high density linkage map and QTL map** for sex and growth-related traits of common carp (Cyprinus carpio)
Scientific Reports 6: Article number: 26693; published online: 26 May 2016; updated: 22 July 2016 In the original version of this Article, Affiliation 3 was omitted for Wenzhu Peng. The correct affiliations ar...
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Article
Open AccessAn ultra-high density linkage map and QTL map** for sex and growth-related traits of common carp (Cyprinus carpio)
High density genetic linkage maps are essential for QTL fine map**, comparative genomics and high quality genome sequence assembly. In this study, we constructed a high-density and high-resolution genetic li...
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Article
Construction of the BAC Library of Small Abalone (Haliotis diversicolor) for Gene Screening and Genome Characterization
The small abalone (Haliotis diversicolor) is one of the most important aquaculture species in East Asia. To facilitate gene cloning and characterization, genome analysis, and genetic breeding of it, we constructe...
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Article
Convenient Synthesis of Ferrocenylethynyl Ketones via Carbonylative Coupling of Ferrocenylethyne with Aryl Iodides by Using Water as Solvent
Carbonylative coupling reaction of aryl iodides with ferrocenylethyne catalyzed by PdCl2 was carried out using sodium dodecyl sulphonate (SDS) as surfactant and water as solvent. The reaction gave much better yie...
