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Article
Hemodynamic collapse in prone position due to thoracic malformation
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Article
Erratum: Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons
Correction to: Molecular Psychiatry advance online publication, 18 November 2014; doi:10.1038/mp.2014.143 Following publication of this paper, the authors noticed that cell line GM02036 was missing from Supple...
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Article
Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons
Psychiatric disorders have clear heritable risk. Several large-scale genome-wide association studies have revealed a strong association between susceptibility for psychiatric disorders, including bipolar disea...
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Article
Open AccessA phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503)
The Notch signalling pathway has been implicated in tumour initiation, progression, angiogenesis and development of resistance to vascular endothelial growth factor (VEGF) targeting, providing a rationale for ...
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Article
Open AccessA longitudinal pilot proton MRS investigation of the manic and euthymic states of bipolar disorder
Several lines of evidence implicate dysfunction in brain energy production as a key component of bipolar disorder. In particular, elevated brain lactate levels observed in this condition suggest a shift from a...
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Article
Phase I–II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo
In preclinical models, the histone deacetylase inhibitor vorinostat sensitizes breast cancer cells to tubulin-polymerizing agents and to anti-vascular endothelial growth factor-directed therapies. We sought to...
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Article
Losing potential organ donors in critical care units: data from the Donor Action Database
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Article
Critical care staff attitudes to organ donation impact on national donation rates: data from the Donor Action Database
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Article
Decision support frameworks and metrics for sustainable development of minerals and metals
The Australian government-supported Co-operative Research Centre for Sustainable Resource Processing (CSRP) has undertaken a comprehensive review of sustainability metrics and decision support frameworks used ...
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Chapter and Conference Paper
The “FAME” Interactive Space
This paper describes the “FAME” multi-modal demonstrator, which integrates multiple communication modes – vision, speech and object manipulation – by combining the physical and virtual worlds to provide suppor...
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Article
Open AccessA prognostic index for operable, node-negative breast cancer
Clinical data and samples from patients diagnosed, more than 10 years previously, with operable node-negative breast cancer (participants in the Scottish Adjuvant Tamoxifen trial), were revisited. Cases with t...
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Article
Successful mobilization of peripheral blood stem cells after addition of ancestim (stem cell factor) in patients who had failed a prior mobilization with filgrastim (granulocyte colony-stimulating factor) alone or with chemotherapy plus filgrastim
This study assessed the ability of recombinant human stem cell factor (rHuSCF) to mobilize stem cells in 44 patients who had failed a prior mobilization (CD34+ yield 0.5–1.9 × 106/kg BW) with filgrastim-alone or ...
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Article
DNA sequence evidence for speciation, paraphyly and a Mesozoic dispersal of cancellothyridid articulate brachiopods
Because the classification of extant and fossil articulate brachiopods is based largely upon shell characters observable in fossils, it identifies morphotaxa whose biological status can, in practice, best be ...
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Article
Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study
Rationale: Phosphatidylcholine (PtdCho) in brain cell membranes decreases with age. Evidence from both animal and in vitro studies indicates that CDP-choline (citicoline) administration may increase phosphatidylc...
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Article
Vestibular control of sympathetic activity
It has been proposed that a vestibular reflex originating in the otolith organs and other body graviceptors modulates sympathetic activity during changes in posture with regard to gravity. To test this hypothe...
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Article
Engraftment syndrome: a common cause for rash and fever following autologous hematopoietic stem cell transplantation for multiple sclerosis
Autologous hematopoietic stem cell transplantation (HSCT) is currently being evaluated as a therapy for patients with progressive multiple sclerosis (MS) at risk of debilitating neurological impairment. While ...
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Article
Recent advances in the biocontrol of Orobanche (broomrape) species
Parasitic broomrapes (Orobanche spp.) are majoruncontrolled weeds in the Mediterranean regions of Europe and the NearEast causing major losses to vegetable, grain legume, and sunflowercrops. Selective herbicides ...
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Article
Open AccessEvidence of a founder BRCA1 mutation in Scotland
BRCA1 mutations have been identified in breast and ovarian cancer families from diverse ethnic backgrounds. We studied 17 different families with the BRCA1 2800delAA mutation; seven were ascertained in Scotland ...
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Article
Effect of viewing distance on the generation of vertical eye movements during locomotion
Vertical head and eye coordination was studied as a function of viewing distance during locomotion. Vertical head translation and pitch movements were measured using a video motion analysis system (Optotrak 30...
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Article
Abstracts of papers presented at the 15th conference of the weed science society of Israel