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  1. Article

    Open Access

    Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results

    T P Hughes, B Leber, F Cervantes, N Spector, R Pasquini, N C D Clementino… in Leukemia (2017)

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  2. No Access

    Article

    Long-term follow-up of a pilot study using a chemotherapy-alone protocol for killer Ig-like receptor-ligand-mismatched haploidentical haematopoietic SCT

    Advanced haematological malignancies are incurable without allogeneic haematopoietic SCT (HSCT). Many patients do not have a human leukocyte Ag (HLA)-matched donor; hence, haploidentical HSCT has been explored...

    A P Schwarer, G Bollard, M Kapuscinski, J Muirhead… in Bone Marrow Transplantation (2011)

  3. No Access

    Article

    Patients with chronic myeloid leukemia who maintain a complete molecular response after stop** imatinib treatment have evidence of persistent leukemia by DNA PCR

    Around 40–50% of patients with chronic myeloid leukemia (CML) who achieve a stable complete molecular response (CMR; undetectable breakpoint cluster region-Abelson leukemia gene human homolog 1 (BCR–ABL1) mRNA) o...

    D M Ross, S Branford, J F Seymour, A P Schwarer, C Arthur, P A Bartley… in Leukemia (2010)

  4. No Access

    Chapter

    Calcitonin Receptor Expression in Embryonic, Foetal and Adult Tissues: Developmental and Pathophysiological Implications

    It has been well established that the calcitonin receptor (CTR) mediates the actions of calcitonin in bone homeostatic mechanisms during growth and in adulthood. However, the widespread expression of CTR in em...

    P.J. Wookey, A. Zulli, C. Lo, D. L. Hare… in The calcitonin gene-related peptide family (2010)

  5. No Access

    Article

    A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation

    We performed a randomized comparison of pre-emptive and empiric antibiotic therapy for adult patients undergoing allogeneic or autologous stem cell transplantation. One hundred and fifty-three patients were ra...

    M A Slavin, A P Grigg, A P Schwarer, J Szer, A Spencer… in Bone Marrow Transplantation (2007)

  6. No Access

    Article

    Successful mobilization of peripheral blood stem cells using recombinant human stem cell factor in heavily pretreated patients who have failed a previous attempt with a granulocyte colony-stimulating factor-based regimen

    To assess the efficacy of recombinant human stem cell factor (rHuSCF), 48 patients who had failed to mobilize >2.0 × 106 CD34+ cells/kg with granulocyte colony-stimulating factor (G-CSF) (10 μg/kg twice daily) wi...

    M A Dawson, A P Schwarer, J L Muirhead, M J Bailey… in Bone Marrow Transplantation (2005)

  7. No Access

    Article

    Optimal scheduling to reduce morbidity of involved field radiotherapy with transplantation for lymphomas: A Prospective Australasian Leukaemia and Lymphoma Group Study

    This study evaluated delivery of involved field radiotherapy (IFRT) with transplantation for lymphomas timed to minimise toxicity. Patients transplanted for lymphoma had infradiaphragmatic disease irradiated p...

    A Wirth, H M Prince, M Wolf, J M Stone, J Matthews, J Gibson… in Bone Marrow Transplantation (2005)

  8. No Access

    Article

    Improved detection of clinically significant host-reactive antigens prior to HLA-identical sibling peripheral blood stem cell transplantation using a dendritic cell-based helper T-lymphocyte precursor assay

    Graft-versus-host disease (GVHD) due to host-reactive antigenic differences between HLA-identical pairs remains an important cause of morbidity and mortality after allogeneic transplantation. The helper T-lymp...

    A P Schwarer, G Healey, M Hammett in Bone Marrow Transplantation (2004)

  9. No Access

    Article

    Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase

    We analyzed molecular responses in 55 newly diagnosed chronic-phase chronic myeloid leukemia (CML) patients enrolled in a phase 3 study (the IRIS trial) comparing imatinib to interferon-alfa plus cytarabine (I...

    S Branford, Z Rudzki, A Harper, A Grigg, K Taylor, S Durrant, C Arthur… in Leukemia (2003)

  10. No Access

    Article

    Cytomegalovirus viral load monitoring after allogeneic bone marrow transplantation in patients receiving antiviral prophylaxis

    Cytomegalovirus viral load measurement is a powerful new tool for monitoring of CMV disease; however, the optimal strategy for use is unknown. Weekly plasma CMV viral loads and CMV-related outcomes were monito...

    B P Howden, A Michaelides, D W Spelman, A Spencer… in Bone Marrow Transplantation (2003)

  11. No Access

    Article

    Successful mobilization of peripheral blood stem cells after addition of ancestim (stem cell factor) in patients who had failed a prior mobilization with filgrastim (granulocyte colony-stimulating factor) alone or with chemotherapy plus filgrastim

    This study assessed the ability of recombinant human stem cell factor (rHuSCF) to mobilize stem cells in 44 patients who had failed a prior mobilization (CD34+ yield 0.5–1.9 × 106/kg BW) with filgrastim-alone or ...

    L B To, J Bashford, S Durrant, J MacMillan, A P Schwarer… in Bone Marrow Transplantation (2003)

  12. No Access

    Article

    Successful Control of Disseminated Scedosporium prolificans Infection with a Combination of Voriconazole and Terbinafine

    Disseminated Scedosporium prolificans infections are almost uniformly fatal because of their resistance to antifungal agents. Recently, synergy between triazoles and terbinafine has been demonstrated against Sced...

    B. P. Howden, M. A. Slavin, A. P. Schwarer… in European Journal of Clinical Microbiology … (2003)