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Open AccessEfficacy and safety of tacrolimus in older adults with ulcerative colitis: a retrospective study
The prevalence of ulcerative colitis (UC) has been increasing, also in older adults. Here, we retrospectively compared the efficacy and safety of tacrolimus (TAC) in older and younger patients with UC.
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Article
Open AccessStatistical model of trajectories of reduced mobility in older people with locomotive disorders: a prospective cohort study with group-based trajectory model
Today we experience “Super-aged society”, and a drastic increase in the number of older people needing assistance is an urgent matter for everyone from medical and socio-economical standpoints.
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Article
Degradation of the endocrine-disrupting 4-nonylphenol by ferrate(VI): biodegradability and toxicity evaluation
4-Nonylphenol (4-NP) is an endocrine-disrupting and persistent chemical and is partially degraded in conventional wastewater treatment processes. Ferrate(VI) can be used as an environment-friendly oxidizing ag...
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Article
Open AccessRelationship between mucosal healing by tacrolimus and relapse of refractory ulcerative colitis: a retrospective study
Tacrolimus (TAC) is a powerful remission-inducing drug for refractory ulcerative colitis (UC). However, it is unclear whether mucosal healing (MH) influences relapse after completion of TAC.We investigated whe...
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Article
Comparison of Lewis Score and Capsule Endoscopy Crohn’s Disease Activity Index in Patients with Crohn’s Disease
Small bowel capsule endoscopy (SBCE) is used to visualize mucosal inflammatory changes in the small intestine of patients with Crohn’s disease (CD). The Lewis score (LS) and Capsule Endoscopy Crohn’s Disease A...
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Article
Open AccessIncidence of postoperative nausea and vomiting is not increased by combination of low concentration sevoflurane and propofol compared with propofol alone in patients undergoing laparoscopic gynecological surgery
The incidence of postoperative nausea and vomiting (PONV) is higher in patients receiving volatile anesthetics than those receiving total intravenous anesthesia (TIVA) with propofol. However, it is unclear whe...
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Article
A case of gastrojejunocolic fistula with steatohepatitis
A man in his 30s, who had undergone retrocolic Billroth II reconstruction for perforated duodenal ulcer, presented with watery diarrhea for 2 years and suspected fatty liver. He was referred to our hospital fo...
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Article
Tongue Pressure During Swallowing in Adults with Down Syndrome and Its Relationship with Palatal Morphology
In individuals with Down syndrome, hypotonicity of the tongue and an underdeveloped maxilla may lead to poor oral motor coordination, which adversely affects the oral phase of swallowing. This study aimed to e...
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Evaluating Removal of Radionuclides from Landfill Leachate Using Generally Practiced Wastewater Treatment Processes
Some amounts of the radionuclides released in the nuclear accident at the Fukushima Daiichi Nuclear Power Plant are transferred to wastes such as sewage sludge ash and municipal waste ash. Among these wastes, ...
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Article
Inhibition of macrophage activation and suppression of graft rejection by DTCM-glutarimide, a novel piperidine derived from the antibiotic 9-methylstreptimidone
We have previously synthesized a novel piperidine compound, 3-[(dodecylthiocarbonyl)methyl]glutarimide (DTCM-glutarimide), that inhibits LPS-induced NO production, and in the present research we studied furthe...