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  1. Article

    Open Access

    Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells

    In space, cells sustain strong modifications of their mechanical environment. Mechanosensitive molecules at the cell membrane regulate mechanotransduction pathways that induce adaptive responses through the re...

    Nancy Garbacki, Jérôme Willems, Thibaut Neutelings, Charles Lambert in npj Microgravity (2023)

  2. Article

    Open Access

    Rapid adaptation to microgravity in mammalian macrophage cells

    Despite the observed severe effects of microgravity on mammalian cells, many astronauts have completed long term stays in space without suffering from severe health problems. This raises questions about the ce...

    Cora S. Thiel, Diane de Zélicourt, Svantje Tauber, Astrid Adrian in Scientific Reports (2017)

  3. Article

    Open Access

    The oxidative burst reaction in mammalian cells depends on gravity

    Gravity has been a constant force throughout the Earth’s evolutionary history. Thus, one of the fundamental biological questions is if and how complex cellular and molecular functions of life on Earth require ...

    Astrid Adrian, Kathrin Schoppmann, Juri Sromicki in Cell Communication and Signaling (2013)