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Article
Open AccessSynaptic mechanisms underlying onset and progression of memory deficits caused by hippocampal and midbrain synucleinopathy
Cognitive deficits, including working memory, and visuospatial deficits are common and debilitating in Parkinson’s disease. α-synucleinopathy in the hippocampus and cortex is considered as the major risk facto...
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Article
Open AccessEffects of uremic toxins on hippocampal synaptic transmission: implication for neurodegeneration in chronic kidney disease
Patients affected by chronic kidney disease (CKD) have an increased risk of develo** cognitive impairment. The cause of mental health disorders in CKD and in chronic hemodialysis patients is multifactorial, ...
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Article
Open AccessErratum: Persistent activation of microglia and NADPH oxidase drive hippocampal dysfunction in experimental multiple sclerosis
Scientific Reports 6: Article number: 20926; published online: 18 February 2016; updated: 13 April 2016 The original version of this Article contained an error in the title of the paper, where “Persistent acti...
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Article
Open AccessPersistent activation of microglia and NADPH oxidase drive hippocampal dysfunction in experimental multiple sclerosis
Cognitive impairment is common in multiple sclerosis (MS). Unfortunately, the synaptic and molecular mechanisms underlying MS-associated cognitive dysfunction are largely unknown. We explored the presence and ...
