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Article
Open AccessReceptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target
Receptor tyrosine kinases (RTK) are potential targets for the treatment of ischemic heart disease. The human RTK family consists of 55 members, most of which have not yet been characterized for expression or a...
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Article
Open AccessPolysialic acid is associated with better prognosis and IDH1-mutation in diffusely infiltrating astrocytomas
The aim of the study was to assess the localization of Polysialic acid (polySia) and Neural cell adhesion molecule (NCAM) in grade I–IV astrocytomas by confocal microscopy, and also to clarify and compare thei...
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Article
Open AccessAbsence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma
The expression of a neural crest stem cell marker, polysialic acid (polySia), and its main carrier, neural cell adhesion molecule (NCAM), have been detected in some malignant tumors with high metastatic activi...