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Open AccessCombined genetic and chemical screens indicate protective potential for EGFR inhibition to cardiomyocytes under hypoxia
The return of blood flow to ischemic heart after myocardial infarction causes ischemia–reperfusion injury. There is a clinical need for novel therapeutic targets to treat myocardial ischemia–reperfusion injury...
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Open AccessReceptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target
Receptor tyrosine kinases (RTK) are potential targets for the treatment of ischemic heart disease. The human RTK family consists of 55 members, most of which have not yet been characterized for expression or a...