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11 Result(s)
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Article
Open AccessInterstitial lung abnormalities and interstitial lung diseases associated with cigarette smoking in a rural cohort undergoing surgical resection
Cigarette smoking is a risk factor for interstitial lung abnormalities (ILAs) and interstitial lung diseases (ILDs). Investigation defining the relationships between ILAs/ILDs and clinical, radiographic, and p...
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Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice
Prolonged exposure to high oxygen concentrations in premature infants, although lifesaving, can induce lung oxidative stress and increase the risk of develo** BPD, a form of chronic lung disease. The lung al...
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Open AccessFactors associated with self-reported health: implications for screening level community-based health and environmental studies
Advocates for environmental justice, local, state, and national public health officials, exposure scientists, need broad-based health indices to identify vulnerable communities. Longitudinal studies show that ...
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Article
Anemia and global iron fortification and supplementation
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Pneumoconiosis in the Twenty-First Century
While defined pathologically, it is uncommon that the diagnosis of pneumoconiosis necessitates tissue biopsy. The approach initially used by physicians for diagnosis of asbestosis has been extrapolated to all ...
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Article
Open AccessHepcidin expression in human airway epithelial cells is regulated by interferon-γ
Hepcidin serves as a major regulator of systemic iron metabolism and immune function. Airway epithelial cells have an extensive interface with the environment, and so must be able to respond locally to the pre...
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Open AccessIron homeostasis and oxidative stress in idiopathic pulmonary alveolar proteinosis: a case-control study
Lung injury caused by both inhaled dusts and infectious agents depends on increased availability of iron and metal-catalyzed oxidative stress. Because inhaled particles, such as silica, and certain infections ...
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Panel discussion review: session four — assessing biological plausibility of epidemiological findings in air pollution research
In December 2006, the U.S. Environmental Protection Agency (EPA) sponsored a 2-day workshop on “Interpretation of Epidemiologic Studies of Multipollutant Exposure and Health Effects” in Chapel Hill, NC. The fi...
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Exercise-Induced Pulmonary Hemorrhage After Running a Marathon
We report on a healthy 26-year-old male who had an exercise-induced pulmonary hemorrhage (EIPH) within 24 hours of running a marathon. There were no symptoms, abnormalities on exam, or radiographic infiltrates...
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Relative Intrinsic Potency of Asbestos and Erionite Fibers: Proposed Mechanism of Action
Data from human exposure to naturally occurring mineral fibers indicates extreme variability in the rate of mesothelioma between various asbestos varieties and erionite. Experiments on rats have confirmed thes...
